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01148

Sigma-Aldrich

Natriumfluorid

puriss., meets analytical specification of Ph. Eur., BP, USP, 98.5-100.5% (calc. to the dried substance)

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About This Item

Lineare Formel:
NaF
CAS-Nummer:
7681-49-4
Molekulargewicht:
41.99
EG-Nummer:
231-667-8
MDL-Nummer:
MFCD00003524
UNSPSC-Code:
12352302
eCl@ss:
38050104
PubChem Substanz-ID:
329747226
NACRES:
NA.21

Dampfdruck

1.4 mmHg ( 0 °C)

Qualitätsniveau

200

Qualität

puriss.
meets analytical specification of Ph. Eur., BP, USP

Assay

98.5-100.5% (calc. to the dried substance)

Form

powder

Verunreinigungen

acidity or alkalinity, complies
 organic volatile impurities, complies (GC)
 residual solvents, complies
≤0.002% heavy metals (as Pb)
≤0.1% free alkali (as NaOH)
≤0.2% free acid (as HF)
≤0.2% sodium hexafluorosilicate (Na2SiF6)

Verlust

≤0.5% loss on drying, 150 °C

mp (Schmelzpunkt)

993 °C (lit.)

Anionenspuren

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤200 mg/kg

Kationenspuren

Fe: ≤50 mg/kg

Eignung

complies for appearance of solution

SMILES String

[F-].[Na+]

InChI

1S/FH.Na/h1H;/q;+1/p-1

InChIKey

PUZPDOWCWNUUKD-UHFFFAOYSA-M

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Allgemeine Beschreibung

Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent. It is the most widely employed preservative for glucose in blood. It has been reported to stabilize hepatic microsomal glucose-6-P phosphohydrolase enzyme.

Anwendung

Sodium fluoride may be employed as fluorination agent in the synthesis of aromatic and aliphatic fluorides, via metathesis. It may be used to prepare the lysis buffer.

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Zusätzliche Gefahrenhinweise

EUH032

Lagerklassenschlüssel

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

A J Lange et al.
The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)
Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of
J G Drachman et al.
The Journal of biological chemistry, 270(10), 4979-4982 (1995-03-10)
c-Mpl is a member of the cytokine receptor superfamily, expressed primarily on hematopoietic cells. Recently, the c-Mpl ligand was cloned and found to have thrombopoietic activity. In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells
Effectiveness of sodium fluoride as a preservative of glucose in blood.
Chan AY, et al.
Clinical Chemistry, 35(2), 315-317 (1989)
Synthesis of fluorides by metathesis with sodium fluoride.
Tullock CW and Coffman DD.
The Journal of Organic Chemistry, 25(11), 2016-2019 (1960)
Hye-Jin Lee et al.
The Kaohsiung journal of medical sciences, 31(6), 303-308 (2015-06-05)
Dental caries preventive agents, such as sodium fluoride (NaF) and bamboo salt (BS), are known to cause cellular growth that is characterized by morphological and gene expression changes. This study was designed to investigate the dual effect of NaF and
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