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Y0001432

Minoxidil für die Systemeignung

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

Minoxidil, 6-(1-Piperidinyl)-2,4-pyrimidindiamin-3-oxid, 6-(1-Piperidinyl)-pyrimidin-2,4-diamin-3-oxid

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About This Item

Empirische Formel (Hill-System):
C9H15N5O
CAS-Nummer:
38304-91-5
Molekulargewicht:
209.25
MDL-Nummer:
MFCD00063409
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329831424
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

minoxidil

Hersteller/Markenname

EDQM

mp (Schmelzpunkt)

272-274 °C (dec.) (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

NC1=CC(=NC(=N)N1O)N2CCCCC2

InChI

1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2

InChIKey

ZIMGGGWCDYVHOY-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Minoxidil for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Aktiviert ATP-aktivierte K+-Kanäle; Vasodilatator; verlangsamt oder stoppt Haarausfall und fördert das Nachwachsen von Haaren.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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Beschreibung
Preisangaben

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

Leider sind derzeit keine COAs für dieses Produkt online verfügbar.

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R L DeVillez
Dermatologic clinics, 8(2), 367-375 (1990-04-01)
Topical minoxidil is a trichogenic agent that stimulates the hair follicle via the vasoactive metabolite minoxidil sulfate without any evidence of antiandrogen activity or an effect on the immune system. Less than 5% of the applied dose is absorbed. The
Alfredo Rossi et al.
Recent patents on inflammation & allergy drug discovery, 6(2), 130-136 (2012-03-14)
Minoxidil, a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth, was first introduced, exclusively as an oral drug, to treat high blood pressure. It was however discovered to have the important side-effect
Susumu Otomo
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 119(3), 167-174 (2002-03-28)
The length and size of hair are depend on the anagen term in its hair cycle. It has been reported that the some cell growth factors, such as VEGF, FGF-5S, IGF-1 and KGF, induce the proliferation of cells in the
J T Sobota
Toxicologic pathology, 17(1 Pt 2), 193-202 (1989-01-01)
Minoxidil is an antihypertensive vasodilator with no known capability of inducing human cardiovascular pathology; however, the compound does cause a late, canine-specific lesion of the right atrium and acute right atrial and ventricular papillary muscle changes. In all the autopsy
D A Sica et al.
Journal of clinical hypertension (Greenwich, Conn.), 3(2), 110-114 (2001-06-21)
Minoxidil is a direct vasodilator that has been in use for over two decades. It is used primarily to reduce blood pressure in hypertensives who have been poorly controlled on various multidrug regimens. Although minoxidil is extremely effective, its usefulness
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