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Merck

E1644

Sigma-Aldrich

Ethylendiamintetraessigsäure Dinatriumsalz Dihydrat

98.5-101.5%, BioUltra

Synonym(e):

Dinatriumethylendiamintetraacetat Dihydrat, EDTA Dinatriumsalz, EDTA-Na2, Edathamil, Edetat Dinatriumsalz Dihydrat, Sequestrene Na2

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About This Item

Empirische Formel (Hill-System):
C10H14N2Na2O8 · 2H2O
CAS-Nummer:
Molekulargewicht:
372.24
Beilstein:
3900609
EG-Nummer:
UNSPSC-Code:
12352107
PubChem Substanz-ID:
NACRES:
NA.77
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Biologische Quelle

synthetic (organic)

Qualitätsniveau

Produktlinie

BioUltra

Assay

98.5-101.5%

Form

powder

Eignung der Reaktion

reagent type: chelator

Verunreinigungen

≤0.005% Phosphorus (P)
≤0.05% NH3
≤0.1% Insoluble matter

pH-Wert

4.0-6.0 (0.1 M in H2O)

mp (Schmelzpunkt)

248 °C (dec.) (lit.)

Löslichkeit

H2O: 0.1 M, clear, colorless

Kationenspuren

Al: ≤0.001%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
Pb: ≤0.001%
Zn: ≤0.0005%

Lagertemp.

room temp

SMILES String

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

InChIKey

OVBJJZOQPCKUOR-UHFFFAOYSA-L

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Allgemeine Beschreibung

Ethylenediaminetetraacetic acid (EDTA) is a substituted diamine[1] and a chelator of metal ions.[2] It has anticoagulant[3] and antibacterial activity.[1] EDTA is an inhibitor of metalloprotease.[2] It evades the undesirable effects of ferric, cupric and manganic ions in bleaching. It blocks cellular division, chlorophyll synthesis and algal biomass production.[1]

Anwendung

Chelatbildner mit divalenten Kationen. Blockiert Enzyme wie Metallproteasen, die für ihre Aktivität divalente Kationen benötigen.

Piktogramme

Health hazardExclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Inhalation - STOT RE 2 Inhalation

Zielorgane

Respiratory Tract

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Modulation of matrix metalloproteinase activity by EDTA prevents posterior capsular opacification
Hazra S, et al.
Molecular Vision, 18, 1701-1701 (2012)
Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction (2013)
Matthew R Miller et al.
Journal of biological methods, 2(3), e23-e23 (2015-10-13)
Over the past two decades, researchers have struggled to efficiently express foreign DNA in primary macrophages, impeding research progress. The applications of lipofection, electroporation, microinjection, and viral-mediated transfer typically result in disruptions in macrophage differentiation and function, low expression levels
Meritxell Espino Guarch et al.
eLife, 7 (2018-01-23)
Age-related hearing loss (ARHL) is the most common sensory deficit in the elderly. The disease has a multifactorial etiology with both environmental and genetic factors involved being largely unknown. SLC7A8/SLC3A2 heterodimer is a neutral amino acid exchanger. Here, we demonstrated
EDTA: the chelating agent under environmental scrutiny
Oviedo C and Rodriguez J
Quimica nova, 26(6), 901-905 (2003)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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