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5,5-Dimethyl-1-Pyrrolin N-Oxid
for ESR-spectroscopy
Synonym(e):
DMPO
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About This Item
Empfohlene Produkte
Qualität
for ESR-spectroscopy
Qualitätsniveau
Assay
≥98.0% (GC)
Form
crystals
Brechungsindex
n20/D 1.496 (lit.)
bp
75 °C/0.4 mmHg (lit.)
mp (Schmelzpunkt)
25-29 °C (lit.)
Dichte
1.015 g/mL at 25 °C (lit.)
Lagertemp.
−20°C
SMILES String
CC1(C)CCC=[N+]1[O-]
InChI
1S/C6H11NO/c1-6(2)4-3-5-7(6)8/h5H,3-4H2,1-2H3
InChIKey
VCUVETGKTILCLC-UHFFFAOYSA-N
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Anwendung
Neuroprotektives Mittel; Stickstoffmonoxid-Spin-Falle. Wird verwendet, um Radikale, die durch enzymatische Acetaldehyd-Oxidation gebildet werden, zu untersuchen. Inkubation von Lymphozyten mit DMPO verringert DNA-Schäden durch NiCl2.
5,5-Dimethyl-1-pyrroline N-oxide is a reagent generally used either as a free-radical spin-trapping agent, or electrophilic component during the synthesis of pyrrolidine derivatives. It may also be considered as 1,3-dipole in cycloaddition processes.
Verpackung
Bottomless glass bottle. Contents are inside inserted fused cone.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
203.0 °F - closed cup
Flammpunkt (°C)
95 °C - closed cup
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The journal of physical chemistry. A, 116(26), 7210-7218 (2012-06-07)
Radical forms of sulfur dioxide (SO(2)), sulfite (SO(3)(2-)), sulfate (SO(4)(2-)), and their conjugate acids are known to be generated in vivo through various chemical and biochemical pathways. Oxides of sulfur are environmentally pervasive compounds and are associated with a number
Free radical biology & medicine, 53(4), 962-973 (2012-05-29)
Complex I is a critical site of O(2)(•-) production and the major host of reactive protein thiols in mitochondria. In response to oxidative stress, complex I protein thiols at the 51- and 75-kDa subunits are reversibly S-glutathionylated. The mechanism of
Journal of biochemistry, 150(2), 173-181 (2011-05-17)
The nicotinamide adenine dinucleotide (NADH)/nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and the xanthine oxidase (XOD) systems generate reactive oxygen species (ROS). In the present study, to characterize the difference between the two systems, the kinetics of ROS generated by both
Nucleic acids research, 40(12), 5477-5486 (2012-03-06)
Oxidative stress-related damage to the DNA macromolecule produces lesions that are implicated in various diseases. To understand damage to DNA, it is important to study the free radical reactions causing the damage. Measurement of DNA damage has been a matter
Free radical biology & medicine, 36(10), 1214-1223 (2004-04-28)
The detection of protein free radicals using the specific free radical reactivity of nitrone spin traps in conjunction with nitrone-antibody sensitivity and specificity greatly expands the utility of the spin trapping technique, which is no longer dependent on the quantum
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