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Merck

105481

Sigma-Aldrich

1,3-Diphenyl-isobenzofuran

97%

Synonym(e):

1,3-Diphenyl-2-benzofuran, 2,5-Diphenyl-3,4-benzofuran

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About This Item

Empirische Formel (Hill-System):
C20H14O
CAS-Nummer:
Molekulargewicht:
270.32
Beilstein:
199922
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22

Qualitätsniveau

Assay

97%

Form

solid

mp (Schmelzpunkt)

128-130 °C (lit.)

Funktionelle Gruppe

phenyl

SMILES String

c1ccc(cc1)-c2oc(-c3ccccc3)c4ccccc24

InChI

1S/C20H14O/c1-3-9-15(10-4-1)19-17-13-7-8-14-18(17)20(21-19)16-11-5-2-6-12-16/h1-14H

InChIKey

ZKSVYBRJSMBDMV-UHFFFAOYSA-N

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Allgemeine Beschreibung

1,3-Diphenylisobenzofuran is a fluorescent dye.1,3-Diphenylisobenzofuran is the model compound in studies of singlet fission.

Anwendung

1,3-Diphenylisobenzofuran(DPBF) was used as a fluorescent probe for detection of superoxide anion radical (O2) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) was used as quencher during the photoinactivation of TA-3 mouse mammary carcinoma cells containing hematoporphyrin. 1,3-Diphenylisobenzofuran(DPBF) was used to study the single crystal molecular structure and solution photophysical properties of DPBF.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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K R Weishaupt et al.
Cancer research, 36(7 PT 1), 2326-2329 (1976-07-01)
Singlet oxygen, a metastable state of normal triplet oxygen, has been identified as the cytotoxic agent that is probably responsible for in vitro inactivation of TA-3 mouse mammary carcinoma cells following incorporation of hematoporphyrin and exposure to red light. This
Meng Duan et al.
Nanoscale, 11(39), 18426-18435 (2019-10-03)
This work explored the application of matrix metalloproteinase 2-targeted superparamagnetic nanoprobes for magnetic resonance imaging (MRI), near infrared (NIR) fluorescence imaging and photodynamic therapy of tumors. PEG, PAMAM (G5) and matrix metalloproteinase 2 (MMP2) were attached to the surface of
Diana Zaharie-Butucel et al.
Journal of colloid and interface science, 552, 218-229 (2019-05-28)
Significant efforts are currently being funneled into the improvement of therapeutic outcomes in cancer by designing hybrid nanomaterials that synergistically combine chemotherapeutic abilities and near-infrared (NIR) light-activated photothermal (PTT) and photodynamic (PDT) activity. Herein, a nanotherapeutic platform is specifically designed
T Ohyashiki et al.
Biochimica et biophysica acta, 1421(1), 131-139 (1999-11-16)
Utilization of a fluorescence dye, 1,3-diphenylisobenzofuran (DPBF) as a detector of superoxide anion radical (O2*-) was examined. The fluorescence intensity of DPBF incorporated in phospholipid liposomes consisting of phosphatidylcholine (PC) and phosphatidylserine (PS) is effectively quenched by incubation with xanthine/xanthine
Xingshu Li et al.
Theranostics, 7(10), 2746-2756 (2017-08-19)
A major challenge in photodynamic therapy (PDT) is the development of new tumor-targeting photosensitizers. The tumor-specific activation is considered to be an effective strategy for designing these photosensitizers. Herein, we describe a novel tumor-pH-responsive supramolecular photosensitizer, LDH-ZnPcS

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