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MAB4419A4

Sigma-Aldrich

Anti-OCT-4 [POU5F1] Antibody, clone 7F9.2, Alexa Fluor™ 488 conjugate

clone 7F9.2, from mouse, ALEXA FLUOR™ 488

Synonym(e):

POU domain class 5, transcription factor 1, Octamer-binding protein 3, Oct-3, Octamer-binding protein 4, Oct-4, Octamer-binding transcription factor 3, OTF-3

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Konjugat

ALEXA FLUOR™ 488

Antikörperform

purified antibody

Antikörper-Produkttyp

primary antibodies

Klon

7F9.2, monoclonal

Speziesreaktivität

mouse, human

Methode(n)

immunocytochemistry: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

NP_038661

UniProt-Hinterlegungsnummer

P20263

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... POU5F1(5460)
mouse ... Pou5F1(18999)

Allgemeine Beschreibung

Octamer-4 (Oct-4), a member of the POU family of transcription factors, has been demonstrated to be vital for the formation of self-renewing pluripotent stem cells. During embryogenesis, expression of Oct-4 is limited to pluripotent cells of the inner cell mass (ICM) that contribute to the formation of all fetal cell types. This relationship between Oct-4 and pluripotency has seen this transcription factor emerge as a marker of pluripotent stem cells. Undifferentiated human and murine pluripotent Embryonic Stem (ES) and Embryonic Carcinoma (EC) cells express Oct-4. Additionally, murine Embryonic Germ (EG) cells are also known to express Oct-4. Following stem cell differentiation, the level of Oct-4 expression decreases. Oct-4 has been identified as one of the main transcription factors required to reprogram somatic cells into induced pluripotent stem cells (iPS cells).

Anwendung

Anti-OCT-4 [POU5F1] Antibody, clone 7F9.2, Alexa Fluor 488 conjugate is an antibody against OCT-4 [POU5F1] for use in ICC.

Qualität

Evaluated by Immunocytochemistry in mouse embryonic stem cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected Oct-4 in mouse embryonic stem cells (SCR012).

Zielbeschreibung

The uncojugated parent antibody (Catalog No. MAB4419) has an observed MW at 39 kDa

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

ALEXA FLUOR is a trademark of Life Technologies

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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