94740

Vanadyl-Ribonukleosid-Komplexe

BioReagent, for molecular biology

• Synonym(e): Ribonucleosid-Vanadyl-Komplexe, VRC
• UNSPSC-Code: 12352200
• NACRES: NA.52

Eigenschaften

• Qualität: for molecular biology
• Qualitätsniveau: 100
• Produktlinie: BioReagent
• Form: powder
• Eignung: in accordance for ribonuclease inhibition test
• Versandbedingung: wet ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Vanadyl ribonucleoside complexes are low molecular weight inhibitors of ribonucleases.

Anwendung

Vanadyl ribonucleoside complexes (VDR) are transition state analogs that bind to active sites of many RNases, inhibiting their activity. Because the RNases are not covalently modified by the complexes, VDR must be used at every stage of RNA extraction and purification. However, VDR also inhibit RNA polymerases and in vitro translation and therefore must be removed from final preparation of RNA.

Vanadyl ribonucleoside complexes has been used in hybridization mixture for RNA in situ hybridization.

Biochem./physiol. Wirkung

The vanadyl ribonucleoside complex has the ability to block the formation of ribosomal subunit in Staphylococcus aureus. The complex exhibits anti-microbial activity These complexes also serve as powerful inhibitors of several enzymes with ribonucleolytic activity.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)