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Key Documents

MAB395

Sigma-Aldrich

Anti-Myelin Basic Protein Antibody

CHEMICON®, rat monoclonal, 14

Synonym(e):

MBP

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

product name

Anti-Myelin Basic Protein Antibody, a.a. 36-50, clone 14, culture supernatant, clone 14, Chemicon®

Biologische Quelle

rat

Qualitätsniveau

Antikörperform

culture supernatant

Antikörper-Produkttyp

primary antibodies

Klon

14, monoclonal

Speziesreaktivität (Voraussage durch Homologie)

mammals

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
immunohistochemistry: suitable

Isotyp

IgG2b

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... MBP(4155)

Spezifität

Reacts with a synthetic peptide corresponding to human MBP sequence 36-50 as well as intact human MBP. Numbering of MBP residues is as described by Martenson (1984). Mapped by Geyson method to FFGGDR and RFFGGO region.

Immunogen

Bovine myelin basic protein.
Epitope: a.a. 36-50

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neuronen- & Gliamarker

Neurochemie & Neurotrophine
Detect Myelin Basic Protein using this Anti-Myelin Basic Protein Antibody, a.a. 36-50, clone 14 validated for use in ELISA, IH.
Immunohistochemistry (frozen sections)

ELISA

This antibody is also expected to work for Western blot. Specific testing has not been performed.

Optimal working dilutions must be determined by end user.

Verlinkung

Replaces: MAB395

Physikalische Form

Tissue culture supernatant. Liquid containing 0.09% sodium azide.

Lagerung und Haltbarkeit

Maintain at -20° in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze-thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Feng Mei et al.
Nature medicine, 20(8), 954-960 (2014-07-07)
Functional screening for compounds that promote remyelination represents a major hurdle in the development of rational therapeutics for multiple sclerosis. Screening for remyelination is problematic, as myelination requires the presence of axons. Standard methods do not resolve cell-autonomous effects and
Anzari Atik et al.
Frontiers in physiology, 10, 990-990 (2019-08-21)
Caffeine is one of the few treatments available for infants with apnea of prematurity. As the recommended dosing regimen is not always sufficient to prevent apnea, higher doses may be prescribed. However, little is currently known about the impact of
Chrysanthy Ikonomidou et al.
Neurobiology of disease, 130, 104489-104489 (2019-06-09)
Sedatives and anesthetics can injure the developing brain. They cause apoptosis of neurons and oligodendrocytes, impair synaptic plasticity, inhibit neurogenesis and trigger long-term neurocognitive deficits. The projected vulnerable period in humans extends from the third trimester of pregnancy to the
So-ichi Tamai et al.
The Journal of biological chemistry, 289(3), 1629-1638 (2013-11-28)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of motor neurons. Here we show that the basic leucine zipper transcription factor NFIL3 (also called E4BP4) confers neuroprotection in models of ALS. NFIL3 is up-regulated in primary
Sharmony B Kelly et al.
Journal of neuroinflammation, 18(1), 189-189 (2021-09-02)
Increased systemic and tissue levels of interleukin (IL)-1β are associated with greater risk of impaired neurodevelopment after birth. In this study, we tested the hypothesis that systemic IL-1 receptor antagonist (Ra) administration would attenuate brain inflammation and injury in near-term

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