5.09455

Etomoxir

≥98% (HPLC), liquid, CPT-1 inhibitor, Calbiochem^®

• Synonym(e): InSolution Etomoxir, R(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt hydrate
• Empirische Formel (Hill-System): C₁₅H₁₈ClO₄ · Na
• CAS-Nummer: 828934-41-4
• Molekulargewicht: 320.74
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• product name: Etomoxir, InSolution, ≥98%, 50 mM aqueous solution, shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity
• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: liquid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; avoid repeated freeze/thaw cycles; protect from light
• Lagertemp.: −70°C
• InChI: 1S/C15H19ClO4.Na/c16-12-5-7-13(8-6-12)19-10-4-2-1-3-9-15(11-20-15)14(17)18;/h5-8H,1-4,9-11H2,(H,17,18);/q;+1/p-1/t15-;/m1./s1
• InChIKey: RPACBEVZENYWOL-XFULWGLBSA-M

Beschreibung

Allgemeine Beschreibung

A cell-permeable, irreversible, and stereospecific compound that is shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity in the mitochondria of rat heart H9c2 myoblastic cells at a concentration of 1-80 µM and 40 µM, respectively.

Biochem./physiol. Wirkung

Primary Target
CPT1

Verpackung

Packaged under inert gas

Warnhinweis

Toxicity: Standard Handling (A)

Physikalische Form

A 50 mM (2 mg/118 µL) solution of Etomoxir (Cat. No. 236020) in H₂O.

Rekonstituierung

Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.

Sonstige Hinweise

Xu, F.Y., et al. 2003. J. Lipid Res.44, 415.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable