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07-594

Sigma-Aldrich

Anti-Histone H2A.Z Antibody

serum, Upstate®

Synonym(e):

Anti-H2A.Z-1, Anti-H2A.z, Anti-H2A/z, Anti-H2AFZ, Anti-H2AZ

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human

Verpackung

antibody small pack of 25 μL

Hersteller/Markenname

Upstate®

Methode(n)

western blot: suitable

Isotyp

IgG

UniProt-Hinterlegungsnummer

Versandbedingung

ambient

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... H2AFZ(3015)

Spezifität

Broad species cross-reactivity is expected
C-terminus of histone H2A.Z

Immunogen

peptide containing the sequence SLIGKKGQQ, corres-ponding to the C-terminus of human histone H2A.Z

Anwendung

Research Category
Epigenetik & nukleäre Funktionen
Research Sub Category
Histone
Detect Histone H2A.Z also known as H2AZ histone with Anti-Histone H2A.Z Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.

Qualität

routinely evaluated by immunoblot on acid extracted proteins from HeLa cells and recombinant Histone H2A.Z (Catalog #14-597), no cross-reactivity with Histone H2A

Zielbeschreibung

16kDa

Physikalische Form

Serum
0.05% sodium azide before the addition of glycerol to 30%

Lagerung und Haltbarkeit

2 years at -20°C

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

H2A.Z overexpression promotes cellular proliferation of breast cancer cells.
Amy Svotelis,Nicolas Gevry,Gilles Grondin,Luc Gaudreau
Cell Cycle null
Molecular cloaking of H2A.Z on mortal DNA chromosomes during nonrandom segregation.
Yang Hoon Huh,James L Sherley
Stem Cells null
Chunyuan Jin et al.
Nature genetics, 41(8), 941-945 (2009-07-28)
To understand how chromatin structure is organized by different histone variants, we have measured the genome-wide distribution of nucleosome core particles (NCPs) containing the histone variants H3.3 and H2A.Z in human cells. We find that a special class of NCPs
Zenab F Mchaourab et al.
Scientific data, 5, 180030-180030 (2018-03-07)
The human K562 chronic myeloid leukemia cell line has long served as an experimental paradigm for functional genomic studies. To systematically and functionally annotate the human genome, the ENCODE consortium generated hundreds of functional genomic data sets, such as chromatin
Characterization of the stability and folding of H2A.Z chromatin particles: implications for transcriptional activation.
Abbott, D W, et al.
The Journal of Biological Chemistry, 276, 41945-41949 (2001)

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