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05-829X-555

Sigma-Aldrich

Anti-α-Tubulin Antibody, Alexa Fluor™ 555 conjugate

clone DM1A, from mouse, ALEXA FLUOR™ 555

Synonym(e):

Anti-B-ALPHA-1, Anti-LIS3, Anti-TUBA3

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Konjugat

ALEXA FLUOR™ 555

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

DM1A, monoclonal

Speziesreaktivität

pig, guinea pig, human, avian, mouse, bovine, rat

Hersteller/Markenname

Chemicon®
Upstate®

Methode(n)

immunofluorescence: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

NM_006009

UniProt-Hinterlegungsnummer

Q71U36

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... TUBA1A(7846)

Spezifität

Recognizes α-Tubulin

Immunogen

The epitope recognized by this antibody has been mapped to amino acids 426-450 (AALEKDYEEVGVDSV-EGEGEEEGEE).

Anwendung

Research Category
Zellstruktur
Research Sub Category
Cytoskelett
Anti-α-Tubulin Antibody, Alexa Fluor 555 conjugate detects level of α-Tubulin & has been published & validated for use in IF.

Qualität

Routinely evaluated by immunofluorescence

Zielbeschreibung

50-60 kDa

Physikalische Form

Protein G Purified
Protein G purified immunoglobulin conjugated to Alexa Fluor™ 555. Liquid in PBS containing 1% BSA, 0.05% Tween-20 and 0.05% sodium azide.

Lagerung und Haltbarkeit

Maintain at 4°C for up to one year from date of receipt.

Rechtliche Hinweise

ALEXA FLUOR is a trademark of Life Technologies
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

New microtubule/tubulin-targeted anticancer drugs and novel chemotherapeutic strategies.
Wilson, L and Jordan, M A
Journal of Chemotherapy (Florence, Italy), 16 Suppl 4, 83-85 (2004)
Sungjin Park et al.
STAR protocols, 4(4), 102562-102562 (2023-09-10)
Traditionally, midbody remnants (MBRs) are isolated from cell culture medium using ultracentrifugation, which is expensive and time consuming. Here, we present a protocol for isolating MBRs or large extracellular vesicles (EVs) from mammalian cell culture using either 1.5% polyethylene glycol
Crystallographic structure of tubulin: implications for dynamics and drug binding.
Downing, K H and Nogales, E
Cell Structure and Function, 24, 269-275 (1999)
Erich J Kushner et al.
Molecular biology of the cell, 27(12), 1911-1920 (2016-04-22)
Blood vessel formation requires dynamic movements of endothelial cells (ECs) within sprouts. The cytoskeleton regulates migratory polarity, and centrosomes organize the microtubule cytoskeleton. However, it is not well understood how excess centrosomes, commonly found in tumor stromal cells, affect microtubule

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