890704C

18:1 EPC (Cl Salt)

Avanti Research^™ - A Croda Brand 890704C

• Synonym(e): 1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)
• Empirische Formel (Hill-System): C₄₆H₈₉NO₈PCl
• CAS-Nummer: 474945-24-9
• Molekulargewicht: 850.63
• MDL-Nummer: MFCD22495359
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Form: liquid
• Verpackung: pkg of 1 × 2.5 mL (890704C-25mg); pkg of 1 × 4 mL (890704C-100mg); pkg of 2 × 4 mL (890704C-200mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 890704C
• Konzentration: 10 mg/mL (890704C-25mg); 25 mg/mL (890704C-100mg); 25 mg/mL (890704C-200mg)
• Lipid-Typ: transfection; cationic lipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)OCC.[Cl-]
• InChIKey: LXTQBOAODSPEHG-NATHRRJOSA-M

Beschreibung

Allgemeine Beschreibung

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) is a cationic alkylated phospholipid.[1]

Anwendung

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt) (18:1 EPC (Cl Salt)) is suitable:

• for composing lipid shell to prepare lipopolyplex/mRNA vaccine[2]
• in solvent-assisted preparation of supported lipid bilayers[3]
• along with 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) in mixed liposomes as colloidal vectors for physicochemical study of the DNA compaction[1]
• to formulate the lipid nanoparticle (LNP1) to enhance intracellular delivery mediated by shock waves[4]

Biochem./physiol. Wirkung

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) serves as a transfection reagent. 18:1 EPC is applicable in liposomes and lipoplexes. It is a potential vector in gene therapy.[1]

Verpackung

5 mL Clear Glass Sealed Ampule (890704C-100mg)

5 mL Clear Glass Sealed Ampule (890704C-200mg)

5 mL Clear Glass Sealed Ampule (890704C-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H302,H315,H319,H331,H336,H351,H361d,H372
• P-Sätze: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Zielorgane: Liver,Kidney, Respiratory system
• Lagerklassenschlüssel: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): does not flash
• Flammpunkt (°C): does not flash