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Key Documents

700126P

Avanti

campesterol

Avanti Research™ - A Croda Brand 700126P, powder

Synonym(e):

campest-5-en-3β-ol

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About This Item

Empirische Formel (Hill-System):
C28H48O
CAS-Nummer:
474-62-4
Molekulargewicht:
400.68
UNSPSC-Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

Form

powder

Verpackung

pkg of 1 × 1 mg (700126P-1mg)
pkg of 1 × 10 mg (700126P-10mg)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 700126P

Versandbedingung

dry ice

Lagertemp.

−20°C

InChI

1S/C28H48O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h9,18-20,22-26,29H,7-8,10-17H2,1-6H3

InChIKey

SGNBVLSWZMBQTH-UHFFFAOYSA-N

Verwandte Kategorien

Allgemeine Beschreibung

Campesterol is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure.

Anwendung

Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.

Biochem./physiol. Wirkung

Campesterol reduces the levels of chylomicron, low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL)-apoB100. A high ratio of campesterol to sitosterol enhances fiber elongation in cotton fibres.

Verpackung

5 mL Amber Glass Screw Cap Vial (700126P-10mg)
5 mL Amber Glass Screw Cap Vial (700126P-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

auch häufig zusammen mit diesem Produkt gekauft

Produkt-Nr.
Beschreibung
Preisangaben

700060P

Desmosterol, Avanti Research™ - A Croda Brand

700062P

stigmasterol, Avanti Research™ - A Croda Brand

700095P

sitosterol, Avanti Research™ - A Croda Brand

700121P

sitostanol, β-sitostanol, powder

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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β-Sitosterol synthetic, ≥95%

Sigma-Aldrich

S1270

β-Sitosterol

Δ 5-avenasterol Avanti Research™ - A Croda Brand

Avanti

700174P

Δ 5-avenasterol

Stigmasterol phyproof® Reference Substance

PHL82658

Stigmasterol

β-Sitosterol ≥70%

Sigma-Aldrich

85451

β-Sitosterol

β-Sitosterol from soybean, ≥96%

Sigma-Aldrich

S9889

β-Sitosterol

Cycloartenol ≥90% (GC)

Sigma-Aldrich

08172

Cycloartenol

Laura Calpe-Berdiel et al.
Atherosclerosis, 203(1), 18-31 (2008-08-12)
Plant sterols and stanols (phytosterols/phytostanols) are known to reduce serum low-density lipoprotein (LDL)-cholesterol level, and food products containing these plant compounds are widely used as a therapeutic dietary option to reduce plasma cholesterol and atherosclerotic risk. The cholesterol-lowering action of
Shasha Deng et al.
Science China. Life sciences, 59(2), 183-193 (2016-01-25)
Phytosterols play an important role in plant growth and development, including cell division, cell elongation, embryogenesis, cellulose biosynthesis, and cell wall formation. Cotton fiber, which undergoes synchronous cell elongation and a large amount of cellulose synthesis, is an ideal model
Michael Igel et al.
Journal of lipid research, 44(3), 533-538 (2003-02-04)
The recent identification of the aberrant transport proteins ABCG5 and ABCG8 resulting in sitosterolemia suggests that intestinal uptake of cholesterol is an unselective process, and that discrimination between cholesterol and plant sterols takes place at the level of sterol efflux
Samantha A Hutchinson et al.
International journal of molecular sciences, 20(13) (2019-07-05)
Low fruit and vegetable consumption and high saturated fat consumption causes elevated circulating cholesterol and are breast cancer risk factors. During cholesterol metabolism, oxysterols form that bind and activate the liver X receptors (LXRs). Oxysterols halt breast cancer cell proliferation
U Klahre et al.
The Plant cell, 10(10), 1677-1690 (1998-10-08)
We have identified the function of the Arabidopsis DIMINUTO/DWARF1 (DIM/DWF1) gene by analyzing the dim mutant, a severe dwarf with greatly reduced fertility. Both the mutant phenotype and gene expression could be rescued by the addition of exogenous brassinolide. Analysis
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