W225207

(−)-trans-Caryophyllen

≥80%, FCC, FG

• Synonym(e): β-Caryophyllen, trans-(1R,9S)-8-Methylen-4,11,11-trimethylbicyclo[7.2.0]undec-4-en
• Empirische Formel (Hill-System): C₁₅H₂₄
• CAS-Nummer: 87-44-5
• Molekulargewicht: 204.35
• FEMA-Nummer: 2252
• Beilstein: 2044564
• EG-Nummer: 201-746-1
• CoE-Nummer: 2618
• MDL-Nummer: MFCD00075925
• UNSPSC-Code: 12164502
• PubChem Substanz-ID: 24900952
• Flavis-Nummer: 1.007
• NACRES: NA.21

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 400
• Qualität: FG; Fragrance grade; Halal; Kosher
• Agentur: follows IFRA guidelines; meets purity specifications of JECFA
• Einhaltung gesetzlicher Vorschriften: EU Regulation 1223/2009; EU Regulation 1334/2008 & 178/2002; FCC; FDA 21 CFR 117; FDA 21 CFR 172.515
• Assay: ≥80%
• Optische Aktivität: [α]23/D −7.5°, neat
• Zusammensetzung: contains β-Caryophyllene
• Brechungsindex: n20/D 1.5 (lit.)
• bp: 129-130 °C/14 mmHg (lit.)
• Dichte: 0.901 g/mL at 25 °C (lit.)
• Anwendung(en): flavors and fragrances
• Dokumentation: see Safety & Documentation for available documents
• Nahrungsmittelallergen: no known allergens
• Allergener Duftstoff: β-caryophyllene (ox.)
• Organoleptisch: spicy; woody
• SMILES String: C\C1=C/CCC(=C)[C@H]2CC(C)(C)[C@@H]2CC1
• InChI: 1S/C15H24/c1-11-6-5-7-12(2)13-10-15(3,4)14(13)9-8-11/h6,13-14H,2,5,7-10H2,1,3-4H3/b11-6+/t13-,14-/m1/s1
• InChIKey: NPNUFJAVOOONJE-GFUGXAQUSA-N

Beschreibung

Allgemeine Beschreibung

β;-Caryophyllene is a volatile sesquiterpene compound that can be used as a flavoring agent. It is one of the major volatile organic compounds in Eugenia caryophyllata essential oil, Psidium guajava L. leaves, Arabidopsis thaliana flowers and Artemisia annua L. aerial parts.

Anwendung

• Essential Oil Constituents as Anti-Inflammatory and Neuroprotective Agents: An Insight through Microglia Modulation.: ß-Caryophyllene shows significant potential as an anti-inflammatory and neuroprotective agent by modulating microglia, which plays a crucial role in neuroinflammation (Stojanovic et al., 2024) (Stojanovic et al., 2024).


• Synergistic Antinociceptive Effect of ß-Caryophyllene Oxide in Combination with Paracetamol, and the Corresponding Gastroprotective Activity.: This research demonstrates that ß-caryophyllene oxide, when combined with paracetamol, has enhanced antinociceptive effects and provides gastroprotection (Espinosa-Juárez et al., 2024) (Espinosa-Juárez et al., 2024).


• Consumption of ß-Caryophyllene Increases the Mating Success of Bactrocera zonata Males (Diptera: Tephritidae).: The study explores how ß-caryophyllene consumption boosts the mating success of male fruit flies, indicating its potential applications in pest control strategies (Ul Haq et al., 2024) (Ul Haq et al., 2024).


• Development of ophthalmic nanoemulsions of ß-caryophyllene for the treatment of Acanthamoeba keratitis.: This research focuses on creating nanoemulsions containing ß-caryophyllene for treating Acanthamoeba keratitis, demonstrating its potential in ophthalmic therapies (Santos Porto et al., 2024) (Santos Porto et al., 2024).

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H304,H317
• P-Sätze: P261 - P272 - P280 - P301 + P310 - P302 + P352 - P331
• Gefahreneinstufungen: Asp. Tox. 1 - Skin Sens. 1B
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): 221.9 °F - closed cup
• Flammpunkt (°C): 105.5 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves