L030080

ETT-Aktivator

0.25 M, configured for PerkinElmer, configured for Polygen, configured for MerMade, configured for ABI 3900

• Synonym(e): 5-(Ethylthio)-1H-tetrazol, 5-(Ethylthio)tetrazol-Lösung, 5-Ethylthio-tetrazol -Lösung
• MDL-Nummer: MFCD00068733
• UNSPSC-Code: 41116105
• PubChem Substanz-ID: 329817352
• NACRES: NA.21

Eigenschaften

• Typ: for DNA synthesis
• Produktlinie: Proligo Reagents
• Form: liquid
• Lagerbedingungen: dry at room temperature
• Konzentration: 32-35 g/L (ETT content, titration)
• Verunreinigungen: ≤30 ppm water content (Karl Fischer)
• Farbe: clear
• Kompatibilität: configured for ABI 3900; configured for MerMade; configured for PerkinElmer; configured for Polygen
• SMILES String: CCSc1nnn[nH]1
• InChI: 1S/C3H6N4S/c1-2-8-3-4-6-7-5-3/h2H2,1H3,(H,4,5,6,7)
• InChIKey: GONFBOIJNUKKST-UHFFFAOYSA-N

Beschreibung

Angaben zur Herstellung

Acetonitrile / 5-(Ethylthio)-1H-Tetrazole 100 / 3 (v/w)

Sonstige Hinweise

Activator solution, containing 5-(Ethylthio)-1H- tetrazole (ETT) in acetonitrile, are mixed with solutions of phosphoramidites during the extension step.
The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.

Sicherheitshinweise

• Piktogramme: GHS02,GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H225 - H302 + H312 + H332 - H315 - H318
• P-Sätze: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 35.6 °F - closed cup
• Flammpunkt (°C): 2.0 °C - closed cup