902934

Allyl-poly(ethylene glycol)

average M_n 5,000, PDI <1.3

• Synonym(e): Allyl-PEG-OH, PEG 5k, PEG allyl, Polyethylene glycol
• Lineare Formel: C₃H₅(C₂H₄O)_nOH
• MDL-Nummer: MFCD00020607
• UNSPSC-Code: 12352112
• NACRES: NA.23

Eigenschaften

• Form: powder or solid
• Mol-Gew.: PEG ~5,000 Da; average M_n 5,000
• Farbe: off-white to pale yellow
• PDI: <1.3
• Lagertemp.: 2-8°C
• SMILES String: O(CCO)CC=C
• InChI: 1S/C5H10O2/c1-2-4-7-5-3-6/h2,6H,1,3-5H2
• InChIKey: GCYHRYNSUGLLMA-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.

Anwendung

This heterobifunctional PEG has an allyl functionality on one end and an alcohol on the other. The allyl is commonly used in thiol-ene click chemistry; as well as other ligation reactions.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable