767751

2-{2-[2-(2-Mercaptoethoxy)ethoxy]ethoxy}ethanol

97%

• Synonym(e): MEEE, 1-Mercapto-11-hydroxy-3,6,9-trioxaundecane
• Empirische Formel (Hill-System): C₈H₁₈O₄S
• Molekulargewicht: 210.29
• MDL-Nummer: MFCD22574773
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329767336
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: liquid
• Eignung der Reaktion: reagent type: cross-linking reagent
• Brechungsindex: n20/D 1.481
• Dichte: 1.098 g/mL at 25 °C
• SMILES String: OCCOCCOCCOCCS
• InChI: 1S/C8H18O4S/c9-1-2-10-3-4-11-5-6-12-7-8-13/h9,13H,1-8H2
• InChIKey: GKKYNULPAQDGHI-UHFFFAOYSA-N

Beschreibung

Anwendung

2-{2-[2-(2-Mercaptoethoxy)ethoxy]ethoxy}ethanol may be used in the synthesis of 2-(2-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)ethoxy)ethoxy)ethanol, an nitrobenzoxadiazole (NBD) analog of the anticancer agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX). This analog is a potent glutathione S-transferase (GST) and a potential therapeutic antimelanoma agent with enhanced water solubility and antitumor efficacy when compared to NBDHEX in a study.

• Oligo-ehtylene glycol of peptides and small molecules (PEGylation)
• PEG-disulfide formation
• ultra-thin protein-resistant monolayers
• Densely packed monolayer and a flexible-hydrophilic oligo ethylene glycol arm for avoiding non-specific adsorption

Sicherheitshinweise

• Piktogramme: GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H301,H314
• P-Sätze: P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Gefahreneinstufungen: Acute Tox. 3 Oral - Skin Corr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3