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Merck

767549

Sigma-Aldrich

Poly(ethylene glycol) diacrylate

average Mn 20,000, PEG average Mn 20,000 (n~450), acrylate, ≤1000 ppm MEHQ as inhibitor

Synonym(e):

PEG diacrylate, Polyethylene glycol

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About This Item

UNSPSC-Code:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) diacrylate, average Mn 20,000, contains ≤1000 ppm MEHQ as inhibitor

Form

solid

Qualitätsniveau

Mol-Gew.

PEG average Mn 20,000 (n~450)
average Mn 20,000

Enthält

≤1000 ppm MEHQ as inhibitor

Eignung der Reaktion

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

mp (Schmelzpunkt)

60-65 °C

Ω-Ende

acrylate

α-Ende

acrylate

Polymerarchitektur

shape: linear
functionality: homobifunctional

Lagertemp.

−20°C

Allgemeine Beschreibung

Poly(ethylene glycol) diacrylate (PGEDA) is used for synthesising highly cross-linked hydrogels which are used as biomaterials in tissue engineering. These hydrogels are formed using non-cytotoxic photo initiators. PEG hydrogels can be easily covalently linked to bioactive proteins and peptides which in turn promote specific cell activity either on the surface or within the hydrogel.

Anwendung

This homobifunctional PEG can be used in hydrogel applications; biocompatibilization; thiol-ene coupling; and other applications using cross-linked PEG networks.

Piktogramme

CorrosionExclamation mark

Signalwort

Danger

Gefahreneinstufungen

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Pilnam Kim et al.
Lab on a chip, 6(11), 1432-1437 (2006-10-27)
We present a simple and widely applicable method to fabricate micro- and nanochannels comprised entirely of crosslinked polyethylene glycol (PEG) by using UV-assisted irreversible sealing to bond partially crosslinked PEG surfaces. The method developed here can be used to form
Julia E Leslie-Barbick et al.
Biomaterials, 32(25), 5782-5789 (2011-05-27)
Microvascularization of tissue engineered constructs was achieved by utilizing a VEGF-mimicking peptide, QK, covalently bound to a poly(ethylene glycol) hydrogel matrix. The 15-amino acid peptide, developed by D'Andrea et al., was modified with a PEG-succinimidyl ester linker on the N-terminus
Won-Gun Koh et al.
Langmuir : the ACS journal of surfaces and colloids, 18(7), 2459-2462 (2002-06-29)
We present an easy and effective method for the encapsulation of cells inside PEG-based hydrogel microstructures fabricated using photolithography. High-density arrays of three-dimensional microstructures were created on substrates using this method. Mammalian cells were encapsulated in cylindrical hydrogel microstructures of
Ruohong Shi et al.
Small (Weinheim an der Bergstrasse, Germany), 16(37), e2002946-e2002946 (2020-08-11)
Hydrogels with the ability to change shape in response to biochemical stimuli are important for biosensing, smart medicine, drug delivery, and soft robotics. Here, a family of multicomponent DNA polymerization motor gels with different polymer backbones is created, including acrylamide-co-bis-acrylamide

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