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2-(Diisopropylamino)ethylmethacrylat
97%, contains ~100 ppm monomethyl ether hydroquinone as inhibitor
Synonym(e):
DPA, DPAEMA
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About This Item
Empirische Formel (Hill-System):
C12H23NO2
CAS-Nummer:
Molekulargewicht:
213.32
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12162002
PubChem Substanz-ID:
NACRES:
NA.23
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Qualitätsniveau
Assay
97%
Form
liquid
Enthält
~100 ppm monomethyl ether hydroquinone as inhibitor
Brechungsindex
n20/D 1.145
Dichte
0.900 g/mL at 25 °C
Lagertemp.
2-8°C
SMILES String
CC(C)N(CCOC(=O)C(C)=C)C(C)C
InChI
1S/C12H23NO2/c1-9(2)12(14)15-8-7-13(10(3)4)11(5)6/h10-11H,1,7-8H2,2-6H3
InChIKey
SVYHMICYJHWXIN-UHFFFAOYSA-N
Allgemeine Beschreibung
2-(Diisopropylamino)ethyl methacrylate (DPA) is a methacrylate class of monomer used to prepare various DPA-derived polymers, which includes poly(2-(diisopropylamino)ethyl methacrylate) (PDPA). PDPA is a water-soluble polymer, which exhibits sensitivity to changes in pH and temperature. At pH levels below its pKa value of approximately 6.5, PDPA undergoes a transition from hydrophobic to hydrophilic behavior. This transition is attributed to the protonation of its amino groups. These unique properties of PDPA polymers consequently make them very useful in various applications such as drug delivery, gene delivery, sensors, surfaces, membranes, and chromatography.
Anwendung
2-(Diisopropylamino)ethyl methacrylate can be used:
- As a monomer in the synthesis of multi-responsive hyperbranched copolymers by combining poly(oligo(ethylene glycol)methyl methacrylate) (P(OEGMA)) and 2-(diisopropylamino)ethyl methacrylate (PDIPAEMA) using RAFT polymerization. These polymers find application in drug delivery, gene delivery and tissue engineering.
- A monomers in the synthesis of block copolymer poly(ethyleneglycol)-b-poly(2-(diisopropylamino)ethyl methacrylate) (PEG-b-PDPAEMA). These pH-responsive micelles can be used for enhanced intracellular drug delivery. The DPA monomer contributes to the pH-responsive nature of the copolymers.
Signalwort
Danger
H-Sätze
Gefahreneinstufungen
Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 3
Flammpunkt (°F)
210.0 °F
Flammpunkt (°C)
98.9 °C
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