696641

3,3-Dimethyl-1-(trifluormethyl)-1,2-Benziodoxol

95%

• Synonym(e): 1,3-Dihydro-3,3-dimethyl-1-(trifluormethyl)-1,2-benziodoxol, Togni’s Reagenz
• Empirische Formel (Hill-System): C₁₀H₁₀F₃IO
• CAS-Nummer: 887144-97-0
• Molekulargewicht: 330.09
• MDL-Nummer: MFCD10567056
• UNSPSC-Code: 12352101
• PubChem Substanz-ID: 329761847
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95%
• Form: powder
• Eignung der Reaktion: reaction type: C-C Bond Formation
• mp (Schmelzpunkt): 75-79 °C
• Funktionelle Gruppe: fluoro; iodo
• Lagertemp.: 2-8°C
• SMILES String: CC1(C)O[I](c2ccccc12)C(F)(F)F
• InChI: 1S/C10H10F3IO/c1-9(2)7-5-3-4-6-8(7)14(15-9)10(11,12)13/h3-6H,1-2H3
• InChIKey: HVAPLSNCVYXFDQ-UHFFFAOYSA-N

Beschreibung

Anwendung

Easily accessible hypervalent iodine compound acting as an electrophilic CF₃-transfer reagent for direct, mild, and efficient trifluoromethylation.

Trifluoromethylation of a variety of compounds including:

• Secondary and primary aryl- and alkylphospines
• Phenols
• Peptides containing cysteine residudes by SPPS and electrophilic S-trifluoromethylation
• Arenes and N-heterocycles
• Electrophilic N-trifluoromethylation of Arozoles

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Warning
• H-Sätze: H228,H315,H319,H335
• P-Sätze: P210 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 4.1B - Flammable solid hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves