564990

Ishikawa′s Reagenz

• Synonym(e): N,N-Diethyl-1,1,2,3,3,3-hexafluorpropylamin
• Lineare Formel: CF₃CHFCF₂N(C₂H₅)₂
• CAS-Nummer: 309-88-6
• Molekulargewicht: 223.16
• MDL-Nummer: MFCD00054683
• UNSPSC-Code: 12352101
• PubChem Substanz-ID: 24880211
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Brechungsindex: n20/D 1.3460 (lit.)
• bp: 56-57 °C (lit.)
• Dichte: 1.230 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: amine; fluoro
• SMILES String: CCN(CC)C(F)(F)C(F)C(F)(F)F
• InChI: 1S/C7H11F6N/c1-3-14(4-2)7(12,13)5(8)6(9,10)11/h5H,3-4H2,1-2H3
• InChIKey: BNTFCVMJHBNJAR-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

GC analysis includes Et₂NCF=CFCF₃ (two isomers), both of which are active fluorinating agents.

Anwendung

Reactant for:

• Friedel-Crafts type arylation of hydrofluorocarbons
• Microbial hydroxylation of antibiotics
• Electrochemical fluorination of trialkylamines and tetraalkylammonium salts
• Fluorination of pyrethroides

Reactant for synthesis of:

• γ-Hydroxy-α-fluoro-α-trifluoromethylcarboxamide
• Florfenicol and thiamphenicol

Demonstrates utility in fluorination.

Displays the ability to insert a fluoro(trifluoromethyl) methylene moiety in unsaturated alcohols.

Sicherheitshinweise

• Piktogramme: GHS02,GHS05
• Signalwort: Danger
• H-Sätze: H226,H314
• P-Sätze: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Gefahreneinstufungen: Flam. Liq. 3 - Skin Corr. 1B
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 104.0 °F - closed cup
• Flammpunkt (°C): 40 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles