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Methyl-4-brom-3-methylbenzoat
95%
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About This Item
Empfohlene Produkte
Qualitätsniveau
Assay
95%
mp (Schmelzpunkt)
38-44 °C (lit.)
Funktionelle Gruppe
bromo
ester
SMILES String
COC(=O)c1ccc(Br)c(C)c1
InChI
1S/C9H9BrO2/c1-6-5-7(9(11)12-2)3-4-8(6)10/h3-5H,1-2H3
InChIKey
GTZTYNPAPQKIIR-UHFFFAOYSA-N
Allgemeine Beschreibung
Methyl 4-bromo-3-methylbenzoate, an aromatic ester, undergoes Suzuki coupling with 2-chloroboronic acid to afford the corresponding biaryl.
Anwendung
Methyl 4-bromo-3-methylbenzoate may be used in the preparation of:
It may be used as a starting material in the total synthesis of (-)-martinellic acid.
- 4-bromo-3-vinylbenzoic acid
- 4-bromo-3-(methylphenyl)methanol
- methyl (E)-4-bromo-3-[(phenylmethoxyimino)methyl]benzoate
It may be used as a starting material in the total synthesis of (-)-martinellic acid.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Synthesis and properties of mesogen-jacketed liquid crystalline polymers with asymmetry mesogenic core.
Macromolecules, 40(16), 5718-5725 (2007)
Journal of medicinal chemistry, 48(5), 1314-1317 (2005-03-04)
Allosteric inhibition of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase enzyme has recently emerged as a viable strategy toward blocking replication of viral RNA in cell-based systems. We report here a novel class of allosteric inhibitor of NS5B
The Journal of organic chemistry, 73(12), 4464-4475 (2008-05-14)
The asymmetric total synthesis of martinellic acid, the first pyrrolo[3,2-c]quinoline alkaloid found in nature, is described. Three key steps in our synthesis of (-)-martinellic acid are the Bu(3)SnH-promoted radical addition-cyclization-elimination (RACE) reaction of an oxime ether with an alpha,beta-unsaturated ester
Proceedings of the National Academy of Sciences of the United States of America, 111(46), 16280-16285 (2014-11-08)
For reasons that remain insufficiently understood, the brain requires among the highest levels of metals in the body for normal function. The traditional paradigm for this organ and others is that fluxes of alkali and alkaline earth metals are required
Analytica chimica acta, 985, 91-100 (2017-09-03)
4-Carboxy-benzoboroxole was designed and synthesized. It was then combined with the modification effect of polyethyleneimine (PEI) for the preparation of boronate affinity silica stationary phase. The stationary phase showed improved binding strength with dissociation constant (K
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