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Merck

406546

Sigma-Aldrich

10-Undecinsäure

95%

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About This Item

Lineare Formel:
HC≡C(CH2)8CO2H
CAS-Nummer:
Molekulargewicht:
182.26
Beilstein:
1704918
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22

Qualitätsniveau

Assay

95%

bp

180 °C/15 mmHg (lit.)

mp (Schmelzpunkt)

40-42 °C (lit.)

Funktionelle Gruppe

carboxylic acid

SMILES String

OC(=O)CCCCCCCCC#C

InChI

1S/C11H18O2/c1-2-3-4-5-6-7-8-9-10-11(12)13/h1H,3-10H2,(H,12,13)

InChIKey

OAOUTNMJEFWJPO-UHFFFAOYSA-N

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Allgemeine Beschreibung

10-Undecynoic acid (10- UDYA, UDY) is an acetylenic fatty acid. It is reported as highly selective irreversible inhibitor of hepatic ω- and ω-1-lauric acid hydroxylases. Enzyme catalyzed esterification of 10-undecynoic acid has been reported. UDY has been reported to be synthesized by the dehydrobromination of 10-undecenoic acid.

Anwendung

10-Undecynoic acid was employed as model compound to investigate the microwave assisted surface click reactions catalyzed with Cu(II)/sodium L-ascorbate.†
It may be used:
  • As a biochemical probe in an assay for the microsomal hydroxylation of lauric acid (LA), based on HPLC with flow-through radiochemical detection.
  • To form molecular layers by adsorbing on the fluorite surface.
  • In the supercritical hydrothermal synthesis of iron oxide nanoparticles.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

235.4 °F - closed cup

Flammpunkt (°C)

113 °C - closed cup

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Anna Goc et al.
PloS one, 14(4), e0214763-e0214763 (2019-04-19)
In the search for novel agents against oral pathogens in their planktonic and biofilm form, we have focused our attention on 10-undecynoic acid as the representative of the acetylenic fatty acids. Using macro-broth susceptibility testing method we first established MIC
Fabrizio Cattaruzza et al.
Nucleic acids research, 34(4), e32-e32 (2006-03-02)
Unoxidized crystalline silicon, characterized by high purity, high homogeneity, sturdiness and an atomically flat surface, offers many advantages for the construction of electronic miniaturized biosensor arrays upon attachment of biomolecules (DNA, proteins or small organic compounds). This allows to study
Fengyun Xu et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 283(3), R710-R720 (2002-08-20)
The cytochrome P-450 eicosanoid 20-hydroxyeicosatetraenoic acid (20-HETE) is a potent vasoconstrictor that is implicated in the regulation of blood pressure. The identification of selective inhibitors of renal 20-HETE formation for use in vivo would facilitate studies to determine the systemic
N O Reich et al.
Biochemical pharmacology, 35(8), 1227-1233 (1986-04-15)
Clofibrate, an antilipidemic drug that acts by a still obscure mechanism, is known to specifically increase up to 30-fold the activity of the hepatic cytochrome P-450 isozyme that omega-hydroxlates lauric acid. The thesis that accelerated catabolism of medium-length fatty acids
John Eckelt et al.
Biomacromolecules, 8(6), 1865-1872 (2007-05-25)
Liquid/liquid and liquid/gas equilibria were measured for the water/cellulose system at 80 degrees C using three different polymer samples. For these experiments we prepared cellulose films of approximately 20-25 microm in thickness and determined their equilibrium swelling in water. Thereafter

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