399337

Benzamid

purified by sublimation, ≥99.5%

• Synonym(e): Benzoesäureamid
• Lineare Formel: C₆H₅CONH₂
• CAS-Nummer: 55-21-0
• Molekulargewicht: 121.14
• Beilstein: 385876
• EG-Nummer: 200-227-7
• MDL-Nummer: MFCD00007968
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24864807
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥99.5%
• Form: powder
• Aufgereinigt durch: sublimation
• mp (Schmelzpunkt): 125-128 °C (lit.)
• Löslichkeit: ethanol: soluble 50 mg/mL, clear to slightly hazy, colorless to light yellow
• Funktionelle Gruppe: amide; phenyl
• SMILES String: NC(=O)c1ccccc1
• InChI: 1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
• InChIKey: KXDAEFPNCMNJSK-UHFFFAOYSA-N
• Angaben zum Gen: human ... PARP1(142)

Beschreibung

Allgemeine Beschreibung

Benzamide (Benzoic acid amide, BA) is an amide of benzoic acid. BA on crystallization in benzene (solvent) affords crystals suitable for X-ray analysis. Crystal structure studies suggest that its crystals are monoclinic having space group P2₁/c. Kinetics and mechanism of its reaction with hydrogen peroxide have been proposed.

Anwendung

Benzamide was used to study the mechanism of photocatalytic decomposition of aqueous solution of acetic acid, acetamide and acetonitrile in the presence of semiconductors. Benzamide was used to develop a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.

Biochem./physiol. Wirkung

Inhibiert Poly(ADP-Ribose)-Polymerase (PARP)

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• H-Sätze: H302,H341
• P-Sätze: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Gefahreneinstufungen: Acute Tox. 4 Oral - Muta. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): 356.0 °F - closed cup
• Flammpunkt (°C): 180 °C - closed cup
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves