396788

Ethylformimidat -hydrochlorid

• Synonym(e): Ethyl methanimidate hydrochloride
• Lineare Formel: HC(=NH)OC₂H₅·HCl
• CAS-Nummer: 16694-46-5
• Molekulargewicht: 109.55
• MDL-Nummer: MFCD00192154
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24864683
• NACRES: NA.22

Eigenschaften

• Form: solid
• Qualitätsniveau: 100
• mp (Schmelzpunkt): 75 °C (dec.) (lit.)
• Funktionelle Gruppe: ether
• Lagertemp.: 2-8°C
• SMILES String: Cl.CCOC=N
• InChI: 1S/C3H7NO.ClH/c1-2-5-3-4;/h3-4H,2H2,1H3;1H
• InChIKey: JPUTTYRVDANTBN-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Ethyl formimidate hydrochloride is a nitrogen containing organic building block. On heating it undergoes degradation to afford formamidine hydrochloride, ethyl formate and ethyl chloride.

Anwendung

Ethyl formimidate hydrochloride may be used in the preparation of the following:

• 5-aminoimidazole-4-carboxylic acid α- and β-ribotides
• s-triazines
• 2,3:5,6-di-O-isopropylidene-α- and -β-5-amino-4-ethoxycarbonyl or -carbamoyl-imidazole D-mannofuranosides
• 5-amino-1-(2-pyridyl)imidazole

Reactant involved in the synthesis of biologically active molecules including:

• Bredinin via amination of an acyclic precursor
• Amidine conjugates of the ornithine moiety of an antifungal

Reactant involved in:

• Intermolecular cyclization
• Mo-catalyzed asymmetric ring-closing metathesis for synthesis of cyclid amides and amines
• Synthesis of peptidic 1-cyanopyrrolidines

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves