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Chinazolin
99%
Synonym(e):
1,3-Benzodiazin, Benzopyrimidin
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About This Item
Empirische Formel (Hill-System):
C8H6N2
CAS-Nummer:
Molekulargewicht:
130.15
Beilstein:
109370
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
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Qualitätsniveau
Assay
99%
Form
solid
bp
243 °C (lit.)
mp (Schmelzpunkt)
46-48 °C (lit.)
Löslichkeit
H2O: freely soluble
organic solvents: soluble
SMILES String
c1ccc2ncncc2c1
InChI
1S/C8H6N2/c1-2-4-8-7(3-1)5-9-6-10-8/h1-6H
InChIKey
JWVCLYRUEFBMGU-UHFFFAOYSA-N
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Allgemeine Beschreibung
Quinazolines has applications in medicinal chemistry due to their antibacterial, antifungal, anticonvulsant, anti-inflammatory and antitumor activities. It is the basic structural unit of pharmaceuticals and plays an important role in modern synthesis of antitumor drugs.
Anwendung
Quinazoline was used to study the electrochemical behaviour of quinazoline using modern polarographic and voltammetric methods.
Biochem./physiol. Wirkung
Genotoxicity of quinazoline was established by bacterial SOS Chromotest (Escherichia Coli).
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
222.8 °F - closed cup
Flammpunkt (°C)
106 °C - closed cup
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Polarographic and voltammetric determination of quinazoline-the structural unit of anticancer drugs.
Hladikova J, et al.
Sensing in Electroanalysis, 3, 165-175 (2008)
Reddy Amala et al.
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Current pharmaceutical design, 24(13), 1395-1404 (2018-02-01)
Quinazoline is an aromatic bicyclic compound exhibiting several pharmaceutical and biological activities. This study was conducted to investigate the potential wound healing properties of Synthetic Quinazoline Compound (SQC) on experimental rats. The toxicity of SQC was determined by MTT cell
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