1285750

Flurbiprofen

United States Pharmacopeia (USP) Reference Standard

• 동의어(들): (±)-2-Fluoro-α-methyl-4-biphenylacetic acid, L-790,330
• Linear Formula: C₆H₅C₆H₃(F)CH(CH₃)CO₂H
• CAS Number: 5104-49-4
• Molecular Weight: 244.26
• MDL number: MFCD00079303
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329749901
• NACRES: NA.24

속성

• Grade: pharmaceutical primary standard
• API family: flurbiprofen
• 제조업체/상표: USP
• mp: 110-112 °C (lit.)
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• SMILES string: CC(C(O)=O)c1ccc(c(F)c1)-c2ccccc2
• InChI: 1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)
• InChI key: SYTBZMRGLBWNTM-UHFFFAOYSA-N
• 유전자 정보: human ... PTGS1(5742) , PTGS2(5743)

설명

일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Flurbiprofen USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Flurbiprofen Tablets
• Flurbiprofen Sodium
• Flurbiprofen Sodium Ophthalmic Solution

생화학적/생리학적 작용

Fluibiprofen is a cyclooxygenase (COX) inhibitor, which is an enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This decreases the prostaglandins which cause inflammation, pain, swelling and fever. Flurbiprofen inhibits the activity of both COX-1 and -2. The S enantiomer inhibits prostaglandin synthesis and has both anti-inflammatory and analgesic activity, while the R enantiomer does not inhibit prostaglandin synthesis and displays only analgesic activity.

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable