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Merck
모든 사진(1)

주요 문서

577515-U

Supelco

Discovery® Cyano HPLC Column

5 μm particle size, L × I.D. 2 cm × 3 mm

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모든 사진(1)

About This Item

UNSPSC 코드:
41115700
eCl@ss:
32110501

material

stainless steel column

Agency

suitable for USP L10

제품 라인

Discovery®

특징

endcapped

제조업체/상표

Discovery®

포장

1 ea of

라벨링 범위

4.5% Carbon loading

파라미터

≤70 °C temp. range
400 bar pressure (5801 psi)

기술

HPLC: suitable
LC/MS: suitable

길이 × I.D.

2 cm × 3 mm

표면적

200 m2/g

표면 범위

3.5 μmol/m2

불순물

<10 ppm metals

Matrix

silica gel, high purity, spherical base material
fully porous particle

기질 활성군

cyano phase

입자 크기

5 μm

공극 크기

180 Å

작동 pH 범위

2-8

응용 분야

food and beverages

분리 기술

hydrophilic interaction (HILIC)
normal phase
reversed phase

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특징 및 장점

  • Low hydrophobicity for rapid elution of hydrophobic analytes
  • Excellent peak shape and retention of strongly basic analytes
  • Retention of polar analytes
  • Unique selectivity
  • Significantly less retention than C18 (typically requires lower % organic mobile phase)
  • Stable, low-bleed LC-MS separations
  • Compatible with highly aqueous organic phases

추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

법적 정보

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

E F Nemeth et al.
The Journal of pharmacology and experimental therapeutics, 299(1), 323-331 (2001-09-19)
Despite the discovery of many ions and molecules that activate the Ca2+ receptor, there are no known ligands that block this receptor. Reported here are the pharmacodynamic properties of a small molecule, NPS 2143, which acts as an antagonist at
Aaron D Milstein et al.
Trends in pharmacological sciences, 29(7), 333-339 (2008-06-03)
Presynaptic glutamate release elicits brief waves of membrane depolarization in neurons by activating AMPA receptors. Depending on its precise size and shape, current through AMPA receptors gates downstream processes like NMDA receptor activation and action potential generation. Over a decade
Aleem Gangjee et al.
Journal of medicinal chemistry, 53(22), 8116-8128 (2010-10-27)
Two classes of molecules were designed and synthesized based on a 6-CH(3) cyclopenta[d]pyrimidine scaffold and a pyrrolo[2,3-d]pyrimidine scaffold. The pyrrolo[2,3-d]pyrimidines were synthesized by reacting ethyl 2-cyano-4,4-diethoxybutanoate and acetamidine, which in turn was chlorinated and reacted with the appropriate anilines to
Xuqing Zhang et al.
Journal of medicinal chemistry, 50(16), 3857-3869 (2007-07-20)
A novel series of pyrazolines 2 have been designed, synthesized, and evaluated by in vivo screening as tissue-selective androgen receptor modulators (SARMs). Structure-activity relationships (SAR) were investigated at the R1 to R6 positions as well as the core pyrazoline ring
Graciela B Arhancet et al.
Journal of medicinal chemistry, 53(16), 5970-5978 (2010-08-03)
A new 1,4-dihydropyridine 5a, containing a cyano group at the C3 position, was recently reported to possess excellent mineralocorticoid receptor (MR) antagonist in vitro potency and no calcium channel-blocker (CCB) activity. In the present study, we report the structure-activity relationships
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관련 콘텐츠

Discovery® HPLC Columns for Fast LC-MS Analysis

Discovery® HPLC Columns for Fast LC-MS Analysis. The Discovery LC-MS line offers short length columns for fast LC-MS analysis that are rugged and dependable. Supelco offers a robust product that withstands column shock due to fast gradient turnaround times.

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