These columns are end-capped, but the phase is cyanopropyl.
₩1,373,498
출고 가능일2025년 4월 21일세부사항
추천 제품
제품명
Discovery® Cyano HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
material
stainless steel column
Quality Level
Agency
suitable for USP L10
제품 라인
Discovery®
특징
endcapped
제조업체/상표
Discovery®
포장
1 ea of
라벨링 범위
4.5% Carbon loading
파라미터
≤70 °C temp. range
400 bar pressure (5801 psi)
기술
HPLC: suitable
LC/MS: suitable
길이 × I.D.
15 cm × 4.6 mm
표면적
200 m2/g
표면 범위
3.5 μmol/m2
불순물
<10 ppm metals
Matrix
silica gel, high purity, spherical base material
fully porous particle
기질 활성군
cyano phase
입자 크기
5 μm
공극 크기
180 Å
작동 pH 범위
2-8
응용 분야
food and beverages
분리 기술
hydrophilic interaction (HILIC)
normal phase
reversed phase
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Discovery® Cyano HPLC column is used for the retention and separation of strongly basic analytes including quaternary ammonium salts, with excellent peak shapes.
특징 및 장점
- Low hydrophobicity for rapid elution of hydrophobic analytes
- Excellent peak shape and retention of strongly basic analytes
- Retention of polar analytes
- Unique selectivity
- Significantly less retention than C18 (typically requires lower % organic mobile phase)
- Stable, low-bleed LC-MS separations
- Compatible with highly aqueous organic phases
법적 정보
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Graciela B Arhancet et al.
Journal of medicinal chemistry, 53(16), 5970-5978 (2010-08-03)
A new 1,4-dihydropyridine 5a, containing a cyano group at the C3 position, was recently reported to possess excellent mineralocorticoid receptor (MR) antagonist in vitro potency and no calcium channel-blocker (CCB) activity. In the present study, we report the structure-activity relationships
Srdan Verstovsek et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(3), 788-796 (2008-02-05)
The discovery of an activating somatic mutation in codon 617 of the gene encoding the Janus kinase (JAK)-2 (JAK2 V617F) in patients with myeloproliferative disorders has opened new avenues for the development of targeted therapies for these malignancies. However, no
K Umekawa et al.
Japanese journal of pharmacology, 84(1), 7-15 (2000-10-24)
We describe the pharmacological characteristics of SM-19712 (4-chloro-N-[[(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl)amino]carbonyl] benzenesulfonamide, monosodium salt). SM-19712 inhibited endothelin converting enzyme (ECE) solubilized from rat lung microsomes with an IC50 value of 42 nM and, at 10 - 100 microM, had no effect on other
Christophe Morisseau et al.
Analytical biochemistry, 414(1), 154-162 (2011-03-05)
The microsomal epoxide hydrolase (mEH) plays a significant role in the metabolism of numerous xenobiotics. In addition, it has a potential role in sexual development and bile acid transport, and it is associated with a number of diseases such as
Ye Ding et al.
Chemical communications (Cambridge, England), 47(33), 9495-9497 (2011-07-19)
A novel and facile DDQ-mediated dehydrogenation from natural rigid polycyclic acids or flexible alkyl acids to generate lactones is described. The formation of lactones proceeds by a radical ion mechanism, which has been established by DPPH˙-mediated chemical identification, ESR spectroscopy
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¿Me podrías confirmar que la composición de esta columna es end-capped cyanosilyl silica gel for chromatography R? Gracias!
1 답변-
도움이 되었습니까?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 답변-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
도움이 되었습니까?
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How can I determine the shelf life / expiration / retest date of this product?
1 답변-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf도움이 되었습니까?
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Please provide the below details for the column Carbon loading%- Pore size- Surface area- pH stability- End capping-
1 답변-
TS Answer:
- 4.5% Carbon loading
- Pore size: 180 Å
- Surface area: 200 m2/g
- Operating pH range: 2-8
- Endcapped
- Particle Size: 5 μm
- Temperature Range: ≤70 °C
- Maximum Pressure: 400 bar pressure (5801 psi)
- Suitable for USP L10도움이 되었습니까?
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