V1255
D-Valine
suitable for cell culture, BioReagent
동의어(들):
(R)-α-Aminoisovaleric acid, D-2-Amino-3-methylbutanoic acid
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모든 사진(4)
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1 G
₩51,765
5 G
₩163,314
25 G
₩507,094
About This Item
Linear Formula:
(CH3)2CHCH(NH2)CO2H
CAS Number:
Molecular Weight:
117.15
Beilstein:
1721135
EC Number:
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.75
추천 제품
생물학적 소스
synthetic (organic)
Quality Level
제품 라인
BioReagent
양식
powder
기술
cell culture | mammalian: suitable
mp
>295 °C (subl.) (lit.)
배송 상태
ambient
저장 온도
room temp
SMILES string
CC(C)[C@@H](N)C(O)=O
InChI
1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
InChI key
KZSNJWFQEVHDMF-SCSAIBSYSA-N
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일반 설명
L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine.
애플리케이션
D-Valine has been used as a supplement in:
- Dulbecco′s modified Eagle′s medium (DMEM)/Nutrient Mixture F-12 Ham (F-12) for mice renal proximal tubule cell (RPTC) culture[1]
- endothelial cell growth medium MV2 for rat lung microvascular endothelial cell (RLMEC) culture[2]
- DMEM/F-12 for mouse tracheal epithelial cell (MTEC) culture[3]
생화학적/생리학적 작용
D-Valine has a broad range of industrial applications such as semi-synthetic veterinary antibiotics, pharmaceutical drugs, and agricultural pesticides.[4]
D-valine is used in cell culture as a selective inhibitor of cell proliferation, wherein it inhibits cells that lack the enzyme D-amino acid oxidase. Historically D-valine has been used to inhibit fibroblast growth while allowing selective growth of epithelial cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
S F Gilbert et al.
Cell, 5(1), 11-17 (1975-05-01)
A nutrient medium has been developed to enable the growth of normal epithelial cells while selectively inhibiting fibroblast proliferation. In this medium, D-valine is substituted for L-valine; and only those cells containing D-amino acid oxidase can convert the D-amino acid
Phillip C Calder
The Journal of nutrition, 136(1 Suppl), 288S-293S (2005-12-21)
Although there has been great interest in the effects of amino acids on immune function, little is known about the impact of changes in BCAA availability on the ability of the immune system to function. Human immune cells incorporate BCAA
Ming Chen et al.
World journal of microbiology & biotechnology, 32(10), 171-171 (2016-08-28)
D-Valine is an important organic chiral source and has extensive industrial application, which is used as intermediate for the synthesis of agricultural pesticides, semi-synthetic veterinary antibiotics and pharmaceutical drugs. Its derivatives have shown great activity in clinical use, such as
Hui Li et al.
PLoS pathogens, 14(1), e1006821-e1006821 (2018-01-05)
The highly pathogenic avian influenza (HPAI) H5N1 influenza virus has been a public health concern for more than a decade because of its frequent zoonoses and the high case fatality rate associated with human infections. Severe disease following H5N1 influenza
V A Lazzaro et al.
Research communications in chemical pathology and pharmacology, 75(1), 39-48 (1992-01-01)
A selective cell culture medium, D-valine minimal essential medium (92 mg/l), has been developed to inhibit the proliferation of fibroblasts in cell culture (Gilbert & Migeon 1975). Substitution of D-valine for L-valine prevents fibroblast growth due to the absence of
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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