추천 제품
product name
Transforming Growth Factor-β1 from porcine platelets, TGF-β1, powder, suitable for cell culture
생물학적 소스
Porcine (Platelets)
Quality Level
분석
≥97% (SDS-PAGE)
형태
powder
효능
0.01-0.1 ng/mL ED50/EC50
품질
endotoxin tested
분자량
protein 25 kDa
포장
pkg of 1 μg
pkg of 10 μg
저장 조건
avoid repeated freeze/thaw cycles
기술
cell culture | mammalian: suitable
불순물
≤1 EU/μg
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
pig ... TGFB1(397078)
일반 설명
The TGFB (transforming growth factor-β) gene is mapped to pig (Sus scrofa) chromosome between 6q11-q21. In mammals, TGFβ is present in three isoforms (TGFβ1, TGFβ2 and TGFβ3), of which TGFβ1 is predominant.
애플리케이션
Transforming Growth Factor-β1 from porcine platelets has been used in chondrogenic differentiation. It has also been used in immobilization process.
생화학적/생리학적 작용
Transforming growth factor-β1 (TGF-β) is a multifunctional polypeptide growth factor. TGF-β mediates cell proliferation, differentiation and migration. Important cellular functions such as inflammation, extracellular matrix synthesis, epithelial restoration and developmental processes are also controlled by TGF-β. TGF-β controls the regulation of enamel mineralization in porcine. TGF-β is associated with the development of idiopathic pulmonary fibrosis (a chronic lung disease). TGF-β promotes epithelial-mesenchymal transition (EMT) and contributes to proliferation and metastasis of cancer. The TGF-β induced EMT is observed in kidney fibrosis. TGF-β is stimulates regeneration of intestinal tissue.
Transforming growth factor-β1 (TGF-β1) is produced by many cell types, but is reported to be most concentrated in mammalian platelets, where it is present at approximately four times the level of TGF-β2.
물리적 형태
Lyophilized from a 0.2 μm filtered solution in 35% acetonitrile and 0.1% trifluoroacetic acid containing 0.05 mg bovine serum albumin per μg cytokine.
분석 메모
The biological activity is measured by its ability to inhibit the IL-4-dependent proliferation of mouse HT-2 cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
TGF-β1 autocrine signalling and enamel matrix components
Scientific Reports (2016)
Effect of Conceptus on Transforming Growth Factor (TGF) β1 mRNA Expression and Protein Concentration in the Porcine Endometrium?In Vivo and In Vitro Studies
Journal of Reproduction and Development, 59(6), 512-519 (2013)
Isolation, culture and chondrogenic differentiation of canine
adipose tissue- and bone marrow-derived mesenchymal stem
cells?a comparative study
adipose tissue- and bone marrow-derived mesenchymal stem
cells?a comparative study
Veterinary Research Communications, 36, 139-148 (2012)
Focal adhesion kinase signaling determines the fate of lung epithelial cells in response to TGF-β
American Journal of Physiology. Lung Cellular and Molecular Physiology, 312(6), L926-L935 (2017)
Developmental Changes of TGF-β1 and Smads Signaling Pathway in Intestinal Adaption of Weaned Pigs
PLoS ONE, 9(8) (2014)
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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