추천 제품
생물학적 소스
mouse
재조합
expressed in E. coli
분석
≥95% (HPLC)
≥95% (SDS-PAGE)
양식
lyophilized
분자량
~16.3 kDa
포장
pkg of 50 μg
저장 조건
avoid repeated freeze/thaw cycles
불순물
endotoxin, tested
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
mouse ... Fgf2(14173)
일반 설명
FGF-2 (fibroblast growth factor 2) is a basic heparin binding growth factor.[1] It is ubiquitously expressed and belongs to the FGF family.[2] It is also referred to as BFGF (basic fibroblast growth factor). The recombinant mouse FGF-2 is a single, non-glycosylated chain containing 145 amino acids and having a molecular weight of 16.3kDa.
생화학적/생리학적 작용
FGF-2 (fibroblast growth factor 2, also referred to as BFGF (basic fibroblast growth factor)) stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells.[3][4][5] It is present in the preimplantation embryos and is important for proper development.[6] It is also responsible for angiogenesis.[2] FGF-2 plays a crucial role in adipogenesis and development of adipose tissues.[7] It is associated with tumor growth and metastasis.[8]
물리적 형태
Sterile filtered and Lyophilized without additives.
재구성
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in sterile water to 100 μg/mL.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Blocking FGF2 with a new specific monoclonal antibody impairs angiogenesis and experimental metastatic melanoma, suggesting a potential role in adjuvant settings.
de Aguiar RB
Cancer Letters, 371, 151-160 (2016)
Biphasic effects of FGF2 on adipogenesis.
Kim S
PLoS ONE, 10, e0120073-e0120073 (2015)
Binding of FGF2 to FGFR2 in an autocrine mode in trophectoderm cells is indispensable for mouse blastocyst formation through PKC-p38 pathway.
Yang J
Cell Cycle, 14, 3318-3330 (2015)
Interleukin-1? induces fibroblast growth factor 2 expression and subsequently promotes endothelial progenitor cell angiogenesis in chondrocytes.
Chien SY
Clinical Science, 130, 667-681 (2016)
Yongyi Wang et al.
PloS one, 7(7), e40691-e40691 (2012-08-01)
In fertile women, the endometrium undergoes regular cycles of tissue build-up and regression. It is likely that uterine stem cells are involved in this remarkable turn over. The main goal of our current investigations was to identify slow-cycling (quiescent) endometrial
활성 필터
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