SRP2144
SRC1, receptor interaction domain (627-786), GST tagged human
recombinant, expressed in E. coli, ≥80% (SDS-PAGE)
동의어(들):
F-SRC-1, KAT13A, MGC129719, MGC129720, RIP160, SRC1, bHLHe42, bHLHe74
로그인조직 및 계약 가격 보기
크기 선택
10 μG
₩472,178
모든 사진(1)
크기 선택
보기 변경
10 μG
₩472,178
About This Item
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
생물학적 소스
human
재조합
expressed in E. coli
분석
≥80% (SDS-PAGE)
양식
frozen liquid
분자량
~44 kDa
포장
pkg of 10 μg
저장 조건
avoid repeated freeze/thaw cycles
농도
500 μg/mL
색상
clear colorless
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−70°C
유전자 정보
human ... NCOA1(8648)
1 of 4
이 품목 | SRP2068 | SRP2075 | SRP2064 |
|---|---|---|---|
| biological source human | biological source human | biological source human | biological source human |
| Gene Information human ... NCOA1(8648) | Gene Information human ... NCOA1(8648) | Gene Information human ... NCOA1(8648) | Gene Information human ... NCOA1(8648) |
| recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant expressed in E. coli |
| form frozen liquid | form frozen liquid | form frozen liquid | form frozen liquid |
| concentration 500 μg/mL | concentration 400 μg/mL | concentration 1000 μg/mL | concentration 400 μg/mL |
생화학적/생리학적 작용
Steroid receptor coactivator 1 (SRC1) is a transcriptional coactivator that mediates the activating functions of many of the nuclear hormone receptors. It is also known as NCoA1 and is a member of the SRC/p160 coactivator family. SRC1 is a 160 kDa protein that contains several LXXLL motifs, which are involved in nuclear receptor interaction. The region 627-786 contains 3 LXXLL motifs that are involved in interaction with nuclear hormone receptors and has been previously used in assays detecting ligand-dependent receptor-cofactor interactions.
물리적 형태
Clear and colorless frozen liquid solution
제조 메모
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Jianming Xu et al.
Molecular endocrinology (Baltimore, Md.), 17(9), 1681-1692 (2003-06-14)
The p160 steroid receptor coactivator (SRC) gene family contains three homologous members, which serve as transcriptional coactivators for nuclear receptors and certain other transcription factors. These coactivators interact with ligand-bound nuclear receptors to recruit histone acetyltransferases and methyltransferases to specific
D M Heery et al.
Nature, 387(6634), 733-736 (1997-06-12)
The binding of lipophilic hormones, retinoids and vitamins to members of the nuclear-receptor superfamily modifies the DNA-binding and transcriptional properties of these receptors, resulting in the activation or repression of target genes. Ligand binding induces conformational changes in nuclear receptors
S A Oñate et al.
Science (New York, N.Y.), 270(5240), 1354-1357 (1995-11-24)
A yeast two-hybrid system was used to identify a protein that interacts with and enhances the human progesterone receptor (hPR) transcriptional activity without altering the basal activity of the promoter. Because the protein stimulated transactivation of all the steroid receptors
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
