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Merck
모든 사진(1)

주요 문서

SML3464

Sigma-Aldrich

Gossypetin

≥98% (HPLC)

동의어(들):

2-(3,4-Dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-1-benzopyran-4-one, 8-Hydroxyquercetin, Articulatidin, Equisporol

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크기 선택

5 MG
₩90,741
25 MG
₩366,212

₩90,741


구입 가능 여부는 고객센터에 문의하십시오.

벌크 견적 요청

크기 선택

보기 변경
5 MG
₩90,741
25 MG
₩366,212

About This Item

실험식(Hill 표기법):
C15H10O8
CAS Number:
Molecular Weight:
318.24
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77

₩90,741


구입 가능 여부는 고객센터에 문의하십시오.

벌크 견적 요청

Quality Level

분석

≥98% (HPLC)

양식

powder

색상

, light green to yellow

solubility

DMSO: 2 mg/mL, clear

저장 온도

-10 to -25°C

SMILES string

OC1=CC(O)=C2C(C(O)=C(OC2=C1O)C3=CC=C(C(O)=C3)O)=O

InChI

1S/C15H10O8/c16-6-2-1-5(3-7(6)17)14-13(22)12(21)10-8(18)4-9(19)11(20)15(10)23-14/h1-4,16-20,22H

InChI key

YRRAGUMVDQQZIY-UHFFFAOYSA-N

생화학적/생리학적 작용

Antioxidant, antibacterial, anticancer; potent inhibitor of MKK3 and MKK6 protein kinases
Gossypetin is a hexahydroxylated flavonoid found in the flowers and the calyx of Hibiscus, which exhibits numerous pharmacological effects, including antioxidant, antibacterial and anticancer activities. It induces apoptosis and autophagic cell death in prostate cancer cells. Gossypetin is a potent inhibitor of MKK3 and MKK6 protein kinases that suppresses esophageal cancer growth.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Morgana V Araújo et al.
The Analyst, 144(17), 5232-5244 (2019-07-31)
Leishmaniasis comprises a group of infectious diseases with worldwide distribution, of which both the visceral and cutaneous forms are caused by Leishmania parasites. In the absence of vaccines, efficacious chemotherapy remains the basis for leishmaniasis control. The available drugs are
Xiaomeng Xie et al.
Cancer letters, 442, 126-136 (2018-11-06)
Gossypetin as a hexahydroxylated flavonoid found in many flowers and Hibiscus. It exerts various pharmacological activities, including antioxidant, antibacterial and anticancer activities. However, the anticancer capacity of gossypetin has not been fully elucidated. In this study, gossypetin was found to
Ming-Shih Lee et al.
Molecular carcinogenesis, 56(12), 2578-2592 (2017-07-04)
Gossypetin (GTIN), a naturally occurring hexahydroxy flavone, has been shown to possess antimutagenic, antioxidant, antimicrobial, and antiatherosclerotic effects. Here, we investigated the mechanism(s) underlying the anticancer potential of GTIN. In this study, investigations were showed that GTIN preferentially induces programed

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