SML3181
7,8-Dimethoxyperphenazine
≥98% (HPLC)
동의어(들):
2-(4-(3-((3-chlorophenyl)(3,4-dimethoxyphenyl)amino)propyl)piperazin-1-yl)ethan-1-ol, 4-[3-[8-Chloro-2,3-dimethoxy-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol
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모든 사진(1)
크기 선택
보기 변경
5 MG
₩108,808
25 MG
₩438,785
About This Item
실험식(Hill 표기법):
C23H30ClN3O3S
Molecular Weight:
464.02
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 2 mg/mL, clear
저장 온도
2-8°C
SMILES string
ClC1=CC=C2C(N(CCCN3CCN(CCO)CC3)C(C=C(C(OC)=C4)OC)=C4S2)=C1
InChI key
GKWVWOUUPIERSK-UHFFFAOYSA-N
생화학적/생리학적 작용
7,8-Dimethoxyperphenazine is a cell penetrant inhibitor of UHM (U2AF homology motif) -ULM (U2AF ligand motif) interactions that interacts with the tryptophan binding pocket of different UHM domains including SPF45, PUF60 and U2AF. 7,8-Dimethoxyperphenazine inhibits early spliceosome assembly on pre-mRNA substrates in vitro.
cell penetrant inhibitor of UHM (U2AF homology motif) -ULM (U2AF ligand motif) interactions that interacts with the tryptophan binding pocket of UHM domains
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
Pravin Kumar Ankush Jagtap et al.
Nature communications, 11(1), 5621-5621 (2020-11-08)
Interactions between U2AF homology motifs (UHMs) and U2AF ligand motifs (ULMs) play a crucial role in early spliceosome assembly in eukaryotic gene regulation. UHM-ULM interactions mediate heterodimerization of the constitutive splicing factors U2AF65 and U2AF35 and between other splicing factors
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
