SML2636
Sb4
≥98% (HPLC)
동의어(들):
2-[[(4-Bromophenyl)methyl]thio]benzoxazole, BMP signaling agonist Sb4
로그인조직 및 계약 가격 보기
크기 선택
5 MG
₩106,575
25 MG
₩429,548
모든 사진(1)
크기 선택
보기 변경
5 MG
₩106,575
25 MG
₩429,548
About This Item
실험식(Hill 표기법):
C14H10BrNOS
CAS Number:
Molecular Weight:
320.20
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
분석
≥98% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 2 mg/mL, clear
저장 온도
2-8°C
SMILES string
BrC1=CC=C(CSC2=NC3=C(C=CC=C3)O2)C=C1
InChI
1S/C14H10BrNOS/c15-11-7-5-10(6-8-11)9-18-14-16-12-3-1-2-4-13(12)17-14/h1-8H,9H2
InChI key
JDVOIBFEFVKUPL-UHFFFAOYSA-N
생화학적/생리학적 작용
Cell penetrant, potent bone morphogenetic protein (BMP) signaling agonist that rapidly activate BMP in human renal cells (HEK293)
Sb4 is a cell penetrant, potent bone morphogenetic protein (BMP) signaling agonist that rapidly activate BMP in human renal cells (HEK293). Sb4 activates BMP by stabilization of intracellular p-SMAD-1/5/9. Apparently activation of the BMP pathway by sb4 cannot be reversed by inhibition of Noggin or type I BMP kinase inhibitors
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Shayna T J Bradford et al.
The Journal of biological chemistry, 294(9), 3125-3136 (2019-01-04)
Bone morphogenetic protein (BMP) signaling is critical in renal development and disease. In animal models of chronic kidney disease (CKD), re-activation of BMP signaling is reported to be protective by promoting renal repair and regeneration. Clinical use of recombinant BMPs
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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