SML2486
Peramivir trihydrate
≥98% (HPLC)
동의어(들):
(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic acid trihydrate
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모든 사진(1)
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5 MG
₩154,280
25 MG
₩496,335
About This Item
실험식(Hill 표기법):
C15H28N4O4 · 3H2O
CAS Number:
Molecular Weight:
382.45
UNSPSC 코드:
51111800
NACRES:
NA.77
추천 제품
분석
≥98% (HPLC)
양식
powder
광학 활성
[α]/D -125 to -145°, c = 0.1 in H2O
색상
white to beige
solubility
DMSO: 2 mg/mL, clear
저장 온도
2-8°C
SMILES string
N([C@H]1[C@@H]([C@@H]([C@H](C1)C(=O)O)O)[C@@H](NC(=O)C)C(CC)CC)C(=N)N.O.O.O
InChI
1S/C15H28N4O4.3H2O/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23;;;/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19);3*1H2/t9-,10+,11+,12-,13+;;;/m0.../s1
InChI key
RFUCJKFZFXNIGB-ZBBHRWOZSA-N
생화학적/생리학적 작용
Influenza viral neuraminidase inhibitor
Peramivir exhibits antiviral activity against type A and B influenza virus including pandemic influenza A/H1N1 virus. It also exhibits its antiviral effects on avian influenza viruses like H5N1 and H9N2 strains.[1]
Peramivir is an Influenza viral neuraminidase inhibitor.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
Masanori Kobayashi et al.
Antiviral research, 139, 41-48 (2016-12-26)
High morbidity and mortality associated with human cases of highly pathogenic avian influenza (HPAI) viruses, including H5N1 influenza virus, have been reported. The purpose of the present study was to evaluate the antiviral effects of peramivir against HPAI viruses. In
Zhengtu Li et al.
BMC infectious diseases, 16, 325-325 (2016-07-10)
China-made Peramivir, an anti-influenza neuraminidase inhibitor drug, is manufactured and widely used in China. Although effective if initiated within 48 h of the onset of symptoms, yet we observed that this drug shows an inconclusive efficacy if treatment is delayed in
Jung-Wan Yoo et al.
Journal of medical virology, 87(10), 1649-1655 (2015-05-07)
The clinical efficacy of peramivir in the treatment of severe seasonal influenza in critically ill patients admitted to an intensive care unit (ICU) is not well established. The aim of this study was to compare the clinical efficacy of peramivir
Makoto Kodama et al.
Antiviral research, 109, 110-115 (2014-07-06)
The purpose of this study was to investigate the relationship between pharmacokinetic (PK) parameters of intravenous (IV) peramivir and in vivo antiviral activity pharmacodynamic (PD) outcomes in a mouse model of influenza virus infection. Peramivir was administrated to mice in
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