SML2353

GPR39-C3

≥98% (HPLC)

• 동의어(들): N-[3-Chloro-4-[[[2-(methylamino)-6-(2-pyridinyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide, TC G-1008, TC-G-1008
• 실험식(Hill 표기법): C₁₈H₁₉ClN₆O₂S
• CAS Number: 1621175-65-2
• Molecular Weight: 418.90
• UNSPSC 코드: 12352200

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: CNC1=NC(C2=CC=CC=N2)=CC(NCC3=C(Cl)C=C(NS(C)(=O)=O)C=C3)=N1
• InChI: 1S/C18H19ClN6O2S/c1-20-18-23-16(15-5-3-4-8-21-15)10-17(24-18)22-11-12-6-7-13(9-14(12)19)25-28(2,26)27/h3-10,25H,11H2,1-2H3,(H2,20,22,23,24)
• InChI key: DRSZMILOMUPIBJ-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

GPR39-C3 (TC-G-1008) is an orally available, potent and selective potent agonist of GPR39 that increases GLP-1 secretion in mice. GPR39-C3 exhibits showing an antidepressant-like effect in the forced swim test in mice.

orally available, potent and selective potent agonist of GPR39

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3