SML1962

IWP-O1

≥98% (HPLC)

• 동의어(들): IWP-O1, 5-Phenyl-N-(5-phenylpyridin-2-yl)-4-(pyridin-4-yl)-1H-1,2,3-triazol-1-acetamide, IWP-01
• 실험식(Hill 표기법): C₂₆H₂₀N₆O
• CAS Number: 2074607-48-8
• Molecular Weight: 432.48
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 25 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: [n]3(nnc(c3c5ccccc5)c4ccncc4)CC(=O)Nc1ncc(cc1)c2ccccc2
• InChI key: GYYDQHBKIHQHEB-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

IWP-O1 is an inhibitor of Porcupine (Porcn), an acyl (palmitoyl) transferase essential for secretion of Wnt proteins and involved in both embryonic development and tumor progression. IWP-O1 has good metabolic stability and is extremely potent, exhibiting an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling.

Porcn Inhibitor

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable