SML0563

Docosahexaenoyl ethanolamide

≥98% (HPLC), ethanol solution (5 mg/ml)

• 동의어(들): (4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-Hydroxyethyl)docosa-4,7,10,13,16,19-hexaenamide, DEA, DHEA, N-(2-Hydroxyethyl)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenamide, N-Docosahexaenoylethanolamide
• 실험식(Hill 표기법): C₂₄H₃₇NO₂
• CAS Number: 162758-94-3
• Molecular Weight: 371.56
• UNSPSC 코드: 12352211
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: ethanol solution (5 mg/ml)
• 약물 제어: regulated under CDSA - not available from Sigma-Aldrich Canada
• 색상: colorless to yellow
• 배송 상태: dry ice
• 저장 온도: −20°C

설명

생화학적/생리학적 작용

Docosahexaenoyl ethanolamide (DHEA) has the ability to block the proliferation of head and neck squamous cell carcinoma (HNSCC) cell.[1]

Docosahexaenoyl ethanolamide (DHEA) is a lipid signaling molecule present in brain and retina at concentrations, similar to those for arachidonoyl ethanolamide. DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM. It exhibits anti-inflammatory and organ protective activity. Studies show that docosahexaenoyl ethanolamide is the mediator of neurite growth and synaptogenesis in hippocampal neurons, resulting in enhanced synaptic activity.

Docosahexaenoyl ethanolamide (DHEA), a lipid signaling molecule, binds to the rat brain CB1 receptor and exhibits anti-inflammatory and organ protective activity.

특징 및 장점

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS02,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H319
• 예방조치 성명서: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 55.4 °F
• Flash Point (°C): 13 °C