추천 제품
분석
≥94% (HPLC)
양식
powder
저장 조건
desiccated
색상
white to beige
solubility
DMSO: 0.3 mg/mL, clear (warmed)
저장 온도
−20°C
생화학적/생리학적 작용
FTY20 phosphate (FTY720-P) is a sphingosine 1-phosphate (S1P) receptor agonist and immunomodulatory agent, the active metabolite of FTY720.
FTY20 phosphate (FTY720-P) is a sphingosine 1-phosphate (S1PR) receptor agonist and immunomodulatory agent, the active metabolite of FTY720. FTY720P acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5), with IC50 values of 0.2-6 nM.
특징 및 장점
This compound is featured on the Lysophospholipid Receptors and Lysophospholipid Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Nitai C Hait et al.
Nature neuroscience, 17(7), 971-980 (2014-05-27)
FTY720 (fingolimod), an FDA-approved drug for treatment of multiple sclerosis, has beneficial effects in the CNS that are not yet well understood, independent of its effects on immune cell trafficking. We show that FTY720 enters the nucleus, where it is
문서
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