SML0077
VU591
≥98% (HPLC)
동의어(들):
2,2′-(oxydimethanediyl)bis(5-nitro-1H-benzimidazole), 2,2′-(oxydimethanediyl)bis(6-nitro-1H-benzimidazole), 5-nitro-2-{[(6-nitro-1H-benzimidazol-2-yl)methoxy]methyl}-1H-benzimidazole
로그인조직 및 계약 가격 보기
크기 선택
5 MG
₩143,521
25 MG
₩576,926
모든 사진(1)
크기 선택
보기 변경
5 MG
₩143,521
25 MG
₩576,926
About This Item
실험식(Hill 표기법):
C16H12N6O5
CAS Number:
Molecular Weight:
368.30
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
분석
≥98% (HPLC)
양식
powder
색상
white to tan
solubility
DMSO: ≥12 mg/mL
저장 온도
2-8°C
SMILES string
[O-][N+](=O)c1ccc2nc(COCc3nc4ccc(cc4[nH]3)[N+]([O-])=O)[nH]c2c1
InChI
1S/C16H12N6O5/c23-21(24)9-1-3-11-13(5-9)19-15(17-11)7-27-8-16-18-12-4-2-10(22(25)26)6-14(12)20-16/h1-6H,7-8H2,(H,17,19)(H,18,20)
InChI key
ZQPXNYLXYNRFNP-UHFFFAOYSA-N
유전자 정보
human ... KCNJ1(3758)
애플리케이션
VU591 may be used in cell signaling studies.
생화학적/생리학적 작용
ROMK (Kir 1.1) inhibitor
VU591 is a Potassium Inwardly-Rectifying Channel (KCNJ1 or ROMK) specific inhibitor (IC50 = 240 nM) that is closely related to VU590. Unlike VU590, VU591 does not inhibit Kir7.1. The compound has a modest effect on Kir6.2/SUR1, causing 17% inhibition at 10 uM.
특징 및 장점
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
Jiun-Lin Horng et al.
Scientific reports, 7(1), 16215-16215 (2017-11-28)
Molecular mechanisms of Na
Guglielmo Schiano et al.
Scientific reports, 9(1), 19517-19517 (2019-12-22)
Uromodulin, the most abundant protein in normal urine, is produced by cells lining the thick ascending limb (TAL) of the loop of Henle. Uromodulin regulates the activity of the potassium channel ROMK in TAL cells. Common variants in KCNJ1, the
문서
We offer many products related to potassium channels for your research needs.
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
