SAB4504371

Anti-phospho-Connexin 43 (pSer³⁶⁸) antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-AVSD3, Anti-CMDR, Anti-CX43, Anti-EKVP, Anti-EKVP3, Anti-GJAL, Anti-HLHS1, Anti-HSS, Anti-ODDD, Anti-PPKCA
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 43 kDa
• 종 반응성: human, rat, mouse
• 농도: ~1 mg/mL
• 기술: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI 수납 번호: P17302
• UniProt 수납 번호: P17302
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pSer368)
• 유전자 정보: human ... GJA1(2697)

설명

일반 설명

Connexin 43 (Cx43) is also known as GJA1 (gap junction protein alpha 1) and belongs to a large family of homologous connexin proteins. This protein has an intracellular N-terminus, four transmembrane domains, two extracellular loops, one cytoplasmic loop and an intracellular C-terminus. It is located on human chromosome 6q22-q23.

면역원

The antiserum was produced against synthesized peptide derived from human Connexin 43 around the phosphorylation site of Ser368.

Immunogen Range: 332-381

생화학적/생리학적 작용

Connexin 43 participates in the multiplication and differentiation of mature T cells. This protein also participates in the secretion and manufacturing of cytokines. Mutations in connexin 43 (Cx43) gene result in pleiotropic phenotype of oculodentodigital dysplasia. CX43 helps to release lactate from glycolytic pancreatic ductal adenocarcinoma cells.

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable