추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
whole antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
분자량
antigen 20 kDa (bovine and swine)
포함
15 mM sodium azide
종 반응성
rat, canine, mouse, human, Psammomys (sand rat), sheep, feline, pig, chicken, bovine
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200 using enzyme pre-digested, formalin-fixed, paraffin-embedded human tonsil sections
western blot: 1:200 using mouse thymus extract
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... CD3E(916)
mouse ... Cd3e(12501)
rat ... Cd3e(315609)
일반 설명
CD3 is a 20kDa glycoprotein expressed on surface of all human T lymphocytes. CD3 molecule is encoded by the gene mapped to human chromosome 11q23.3. The CD3 antigen is expressed during thymopoiesis. It is also present in the majority of T-CLL and T-lymphomas and in approximately 70% of T-ALL.
특이성
The antibody reacts with the proline-rich peptide sequence comprising 13 amino acids in the cytoplasmic domain of the CD3-ε chain. It detects normal, reactive and most neoplastic human T cells in routinely processed enzyme pre-digested, formalin-fixed, paraffin-embedded tissue sections. The antibody also reacts with human tissues fixed with Bouin′s solution and embedded in paraffin. Frozen sections and smears are also suitable for staining with this antibody. The antibody reacts with T cell areas in lymphoid tissues derived from various species.
면역원
synthetic human CD3 peptide (residues 156-168 of the CD3-ε chain) coupled to porcine thyroglobulin. Coupling was performed by a modification of the reported method.
애플리케이션
Anti-CD3, T Cell antibody produced in rabbit has been used in:
- immunoblotting
- immunofluorescence staining
- immunohistochemistry
- immunohistochemical analysis
생화학적/생리학적 작용
CD3 is a human cell surface glycoprotein complex involved in signal transduction following binding of antigen receptor.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
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Journal of immunology (Baltimore, Md. : 1950), 188(7), 3138-3149 (2012-03-01)
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Neurobiology of disease, 34(1), 63-70 (2009-01-27)
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Scientific reports, 8(1), 1808-1808 (2018-01-31)
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