PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) is a pleiotropic gene, that codes for a p85α regulatory subunit of phosphatidylinositol-3 kinase (PI3K). This gene is mapped to human chromosome 5q13.
면역원
The antiserum was produced against synthesized peptide derived from human PI3-kinase p85-alpha around the phosphorylation site of Tyr607.
Immunogen Range: 573-622
생화학적/생리학적 작용
PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) is known to mediate immune cell differentiation, development and function. Mutations in PIK3R1 gene result in SHORT syndrome, hyper IgM syndrome, lymphadenopathy and short stature.
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물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Journal of biochemical and molecular toxicology, 37(1), e23220-e23220 (2022-09-13)
We have identified that hydrogen sulfide (H2 S), a gaseous mediator, plays a crucial role in antioxidative, anti-inflammatory, and cytoprotective effects on uranium (U)-triggered rat nephrotoxicity. Pyroptosis is a special mode of inflammation and programmed cell death involved in the
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