SAB4504066

Anti-phospho-SGK (pSer⁷⁸) antibody produced in rabbit

affinity isolated antibody

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 48 kDa
• 종 반응성: human, rat, mouse
• 농도: ~1 mg/mL
• 기술: ELISA: 1:10000; western blot: 1:500-1:1000
• NCBI 수납 번호: O00141
• UniProt 수납 번호: O00141
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pSer78)
• 유전자 정보: human ... SGK1(6446)

설명

일반 설명

The serum and glucocorticoid-regulated kinase (Sgk1) is a member of the AGC kinase family. It is located on human chromosome 6q23. Sgk1 is an aldosterone-induced protein kinase.

면역원

The antiserum was produced against synthesized peptide derived from human SGK around the phosphorylation site of Ser78.

Immunogen Range: 41-90

생화학적/생리학적 작용

The serum- and glucocorticoid-regulated kinase (Sgk1) controls ENaC (expressed renal epithelial Na⁺ channel) by mineralocorticoids. SGK1 controls p27 phosphorylation upon the activation by mTOR-Raptor. This gene is essential to control blood pressure and hypertension in man.

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable