Anti-Keratin 17 antibody detects endogenous levels of total Keratin 17 protein.
Keratin 17/cytokeratin 17 (CK17) is a basal/myoepithelial cell keratin. It is expressed in the respiratory tract, urinary tract and various glands. CK17 is a member of the acidic type I CK family. It is mapped to human chromosome 17q21.
면역원
The antiserum was produced against synthesized peptide derived from human Keratin 17.
Immunogen Range: 381-430
애플리케이션
Anti-Keratin 17, C-Terminal antibody has been used in immunohistochemical staining.
생화학적/생리학적 작용
Keratin 17/cytokeratin 17 (CK17) plays a major role in the development of various human malignancies. It acts as a biomarker in endocervical glandular neoplasia. CK17 is involved in the development of cell and sizing of keratinocytes.
특징 및 장점
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물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Cell death & disease, 7(11), e2452-e2452 (2016-11-04)
Understanding the mechanisms by which cells sense and respond to injury is central to developing therapies to enhance tissue regeneration. Previously, we showed that pancreatic injury consisting of acinar cell damage+β-cell ablation led to islet cell transdifferentiation. Here, we report
Keratin 17 Is a Prognostic Biomarker in Endocervical Glandular Neoplasia
Mockler D, et al.
American Journal of Clinical Pathology, 148(3), 264-273 (2017)