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Merck
모든 사진(2)

주요 문서

SAB4501137

Sigma-Aldrich

Anti-Glucagon antibody produced in rabbit

affinity isolated antibody

동의어(들):

Glicentin, Glicentin-related polypeptide, Glucagon-like peptide 1(7-37), Glucagon-like peptide 1(GLP-1), Oxyntomodulin

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41
제품 SAB4501137은(는)귀하의 국가에서 현재 판매되지 않습니다. 고객지원팀으로 연락바랍니다.

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen 20 kDa

종 반응성

human, rat, mouse

농도

~1 mg/mL

기술

ELISA: 1:5000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... GCG(2641)

일반 설명

Anti-Glucagon antibody detects endogenous levels of total Glucagon protein.
Glucagon-like peptide-1 (GLP-1) is a gastrointestinal hormone. It is a 30-amino acid peptide, that is generated by the intestinal epithelial endocrine L-cells. it is mapped to human chromosome 2q24.

면역원

The antiserum was produced against synthesized peptide derived from human Glucagon.

Immunogen Range: 61-110

애플리케이션

Anti-glucagon antibody has been used in immunostaining and immunohistochemistry.[1]
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

생화학적/생리학적 작용

Glucagon-like peptide-1 (GLP-1) increases glucose-dependent insulin secretion and terminates the liberation of glucagon. It acts as a physiological regulator of appetite and food intake. GLP-1 also helps to prevent the gastrointestinal movement and secretion.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Glucagon-like Peptide-1 Analogues Inhibit Proliferation and Increase Apoptosis of Human Prostate Cancer Cells in vitro
Li XN, et al.
Experimental and Clinical Endocrinology & Diabetes, 125(02), 91-97 (2017)
Maria Eriksson et al.
Molecular pharmaceutics, 18(12), 4428-4436 (2021-10-16)
Type 1 diabetes develops in childhood and adolescence, with peak incidence in the early teenage years. There is an urgent need for an accurate method to detect insulin-producing β-cells in patients that is not affected by alterations in β-cell function.
Reg3? Overexpression Protects Pancreatic Beta-Cells From Cytokine-Induced Damage and Improves Islet Transplant Outcome
Ding Y, et al.
Molecular Medicine, 20(1), 548-548 (2014)
Expression and regulation of chemokines in murine and human type 1 diabetes
Sarkar SA, et al.
Diabetes, 61(2), 436-446 (2012)
Yuichiro Mita et al.
Nature communications, 8(1), 1658-1658 (2017-11-23)
Selenoprotein P (SeP) functions as a selenium (Se)-supply protein. SeP is identified as a hepatokine, promoting insulin resistance in type 2 diabetes. Thus, the suppression of Se-supply activity of SeP might improve glucose metabolism. Here, we develop an anti-human SeP

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