SAB4300623
Anti-Tubulin β-III antibody produced in rabbit
affinity isolated antibody
동의어(들):
Anti-CFEOM3A, Anti-TUBB3, Anti-TUBB4
로그인조직 및 계약 가격 보기
크기 선택
100 μG
₩808,042
₩808,042
구입 가능 여부는 고객센터에 문의하십시오.
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
모든 사진(1)
크기 선택
보기 변경
100 μG
₩808,042
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
₩808,042
구입 가능 여부는 고객센터에 문의하십시오.
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
~55 kDa
종 반응성
mouse, human
농도
1 mg/mL
기술
western blot: 1:500-1:1000
동형
IgG
면역원 서열
(E-E-S-E-A)
NCBI 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... TUBB3(10381)
일반 설명
The antibody detects endogenous level of total Tubulin -βIII protein.
Tubulin β-III (TUBB3) is a constituent of microtubules. It is expressed in mature neurons. It is located on human chromosome 16q24.
면역원
Peptide sequence around aa. 442-446 (E-E-S-E-A), according to the protein NP_006077.2
애플리케이션
Anti-Tubulin β-III antibody has been used in immunocytochemistry and western blot analysis.[1]
생화학적/생리학적 작용
Upregulation of tubulin β-III (TUBB3) shows vigorous tumor characteristics and genetic instability in urinary bladder cancer. It participates in the separation of chromosome. Individuals with congenital fibrosis of the extraocular muscle type 3 (CFEOM3) show mutations in TUBB3. βIII-tubulin modulates glucose metabolism, thereby transforms glucose starvation stress signaling to develop the multiplication of cell and survival in non-small cell lung cancer cells.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
표적 설명
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
물리적 형태
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Directed differentiation of postnatal hippocampal neural stem cells generates nuclear receptor related-1 protein- and tyrosine hydroxylase-expressing cells
Ding Y, et al.
Molecular Medicine Reports, 14(3), 1993-1999 (2016)
Genome-wide gene amplification during differentiation of neural progenitor cells in vitro
Fischer U, et al.
PLoS ONE, 7(5) (2012)
J T Corthell et al.
Neuroscience, 222, 38-48 (2012-07-21)
Circadian rhythms affect olfaction by an unknown molecular mechanism. Independent of the suprachiasmatic nuclei, the mammalian olfactory bulb (OB) has recently been identified as a circadian oscillator. The electrical activity in the OB was reported to be synchronized to a
Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends
Ti SC, et al.
Developmental Cell, 37(1), 72-84 (2016)
?III-tubulin overexpression is linked to aggressive tumor features and genetic instability in urinary bladder cancer
Hinsch A, et al.
Human Pathology, 61, 210-220 (2017)
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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