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Merck
모든 사진(1)

주요 문서

SAB4200191

Sigma-Aldrich

Anti-Septin 9 antibody, Rat monoclonal

clone Clone 1A6C2, purified from hybridoma cell culture

동의어(들):

Anti-MLL, Anti-MSF, Anti-MSF1, Anti-NAPB, Anti-PEANUT-LIKE 4, Anti-PNUTL4, Anti-SEPT9, Anti-SINT1, Anti-SeptD1, Monoclonal Anti-Septin 9 antibody produced in rat

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크기 선택

200 μL
₩857,980

₩857,980


예상 입고일2025년 8월 18일세부사항

기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요

벌크 견적 요청

크기 선택

보기 변경
200 μL
₩857,980

About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

₩857,980


예상 입고일2025년 8월 18일세부사항

기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요

벌크 견적 요청

생물학적 소스

rat

결합

unconjugated

항체 형태

purified from hybridoma cell culture

항체 생산 유형

primary antibodies

클론

Clone 1A6C2, monoclonal

양식

buffered aqueous solution

분자량

~72 kDa

종 반응성

human, rat, monkey, mouse

농도

~1.0 mg/mL

기술

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: 2.5-5.0 μg/mL using L929, HeLa, 3T3 and COS-7 cell extracts

동형

IgG2a

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... SEPT9(10801)
mouse ... Sept9(53860)
rat ... Sept9(83788)

관련 카테고리

일반 설명

Monoclonal Anti-Septin 9 (rat IgG2a isotype) is derived from the hybridoma 1A6C2 produced by the fusion of mouse myeloma cells and splenocytes from rat immunized with a synthetic peptide of corresponding to the N-terminus of rat Septin 9, conjugated to KLH. Septin 9 (SEPT9) is a member of the septin family (also designated MSF/eseptin/Sint1). This gene is mapped to human chromosome 17q25.

면역원

synthetic peptide of corresponding to the N-terminus of rat Septin 9 conjugated to KLH

애플리케이션

Monoclonal Anti-Septin 9 has been used in:
  • immunoblotting
  • immunocytochemistry
  • immunohistochemistry
  • immunofluorescence

생화학적/생리학적 작용

Septin 9 (SEPT9) has been implicated in tumorigenesis. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. In addition, SEPT9 is shown to be a DNA methylation-based biomarker, effectively discriminated colorectal cancer from normal specimens.

물리적 형태

Solution in 0.01M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Taro Tachibana et al.
Hybridoma (2005), 29(2), 169-171 (2010-05-07)
The septin family of GTPase proteins has been shown to be important for cell division, cytoskeletal organization, and membrane-remodeling events. Septin 9 (SEPT9) is a member of the septin family (also designated MSF/eseptin/Sint1) and has been implicated in tumorigenesis. The
Polarity of neuronal membrane traffic requires sorting of kinesin motor cargo during entry into dendrites by a microtubule-associated septin
Karasmanis EP, et al.
Developmental Cell, 46(2), 204-218 (2018)
Eva P Karasmanis et al.
Current biology : CB, 29(13), 2174-2182 (2019-06-18)
Abscission is the terminal step of mitosis that physically separates two daughter cells [1, 2]. Abscission requires the endocytic sorting complex required for transport (ESCRT), a molecular machinery of multiple subcomplexes (ESCRT-I/II/III) that promotes membrane remodeling and scission [3-5]. Recruitment
AML1 amplification and 17q25 deletion in a case of childhood acute lymphoblastic leukemia
Gulten T, et al.
Journal of Clinical Laboratory Analysis, 23(6), 368-371 (2009)
Mutations in SEPT9 cause hereditary neuralgic amyotrophy
Kuhlenbaumer G, et al.
Nature Genetics, 37(10), 1044-1044 (2005)

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